Protein Info for CSW01_04605 in Vibrio cholerae E7946 ATCC 55056

Annotation: LOG family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF14793: DUF4478
  • amino acids 9 to 115 (107 residues), 172.5 bits, E=3.4e-55
• PF03641: Lysine_decarbox
  • amino acids 192 to 330 (139 residues), 109.8 bits, E=1.8e-35
• PF11892: PpnN_C
  • amino acids 335 to 456 (122 residues), 192.8 bits, E=2.9e-61

Best Hits

Swiss-Prot: 70% identical to PPNN_SHIFL: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase (ppnN) from Shigella flexneri

KEGG orthology group: K06966, (no description) (inferred from 100% identity to vcm:VCM66_0856)

MetaCyc: 70% identical to nucleotide 5'-monophosphate nucleosidase (Escherichia coli K-12 substr. MG1655)
AMP nucleosidase. [EC: 3.2.2.4]; Inosinate nucleosidase. [EC: 3.2.2.4, 3.2.2.12]; Pyrimidine-5'-nucleotide nucleosidase. [EC: 3.2.2.4, 3.2.2.12, 3.2.2.10]; 3.2.2.- [EC: 3.2.2.4, 3.2.2.12, 3.2.2.10]

Predicted SEED Role

"Decarboxylase family protein"

MetaCyc Pathways

• adenosine nucleotides degradation III (1/1 steps found)

KEGG Metabolic Maps

• Purine metabolism
• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.2.10 or 3.2.2.12 or 3.2.2.4

Protein Sequence (457 amino acids)

>CSW01_04605 LOG family protein (Vibrio cholerae E7946 ATCC 55056)
MKEDTMIIQVSPAGSMDLLSQLEVERLKKTASSDLYQLYRNCSLAVLNSGSHTDNSKELL
DKYKNFDITVMRRERGIKLELANPPEHAFVDGQIIKGIQEHLFSVLRDIVYVNMHLADSQ
RLNLTNATHITNLVFGILRNAGALIPGATPNLVVCWGGHSINEVEYQYTREVGHELGLRE
LNICTGCGPGAMEGPMKGAAVGHAKQRYSEYRYLGLTEPSIIAAEPPNPIVNELVIMPDI
EKRLEAFVRMAHGIIIFPGGPGTAEELLYILGIMMHPENADQPMPIVLTGPKQSEAYFRS
LDKFITDTLGEAARKHYSIAIDNPAEAARIMSNAMPLVRQHRKDKEDAYSFNWSLKIEPE
FQLPFEPNHESMANLDLHLNQRPEVLAANLRRAFSGVVAGNVKAEGIREIERHGPFEMHG
DPVLMKKMDQLLNDFVAQNRMKLPGGSAYEPCYKIVT