Protein Info for CSW01_04375 in Vibrio cholerae E7946 ATCC 55056

Annotation: SsrA-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 161 PF01668: SmpB" amino acids 15 to 157 (143 residues), 192.7 bits, see alignment E=1.5e-61 TIGR00086: SsrA-binding protein" amino acids 15 to 157 (143 residues), 177.8 bits, see alignment E=6.2e-57

Best Hits

Swiss-Prot: 100% identical to SSRP_VIBC3: SsrA-binding protein (smpB) from Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)

KEGG orthology group: K03664, SsrA-binding protein (inferred from 100% identity to vcm:VCM66_0805)

Predicted SEED Role

"tmRNA-binding protein SmpB" in subsystem Heat shock dnaK gene cluster extended or Staphylococcal pathogenicity islands SaPI or Trans-translation by stalled ribosomes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (161 amino acids)

>CSW01_04375 SsrA-binding protein (Vibrio cholerae E7946 ATCC 55056)
MTKKKTNTKAGSNTIALNKKARHEYFIEDEFEAGMELQGWEVKSLRQGKANIAESYVYIK
DGEAFISGMTIIPLQQASTHVVANPTRIRKLLLSRRELDNLFGRINREGMTLTALSLYWS
RSWVKIKIGVAKGKKLHDKREDLKEKEWQRQKDRVMKSALR