Protein Info for CSW01_04325 in Vibrio cholerae E7946 ATCC 55056

Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 626 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details PF02743: dCache_1" amino acids 36 to 257 (222 residues), 75.7 bits, see alignment E=6e-25 PF00672: HAMP" amino acids 292 to 345 (54 residues), 43.4 bits, see alignment 5.3e-15 PF00015: MCPsignal" amino acids 437 to 589 (153 residues), 135.6 bits, see alignment E=2.4e-43

Best Hits

KEGG orthology group: K10937, accessory colonization factor AcfB (inferred from 100% identity to vco:VC0395_A0365)

Predicted SEED Role

"Accessory colonization factor AcfB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (626 amino acids)

>CSW01_04325 methyl-accepting chemotaxis protein (Vibrio cholerae E7946 ATCC 55056)
MKFSIKLLMIFTSIIITISSILTYFQMHGTNEYLDRTIKDTISETLDSLEDKINLSIESK
VDVSKSVIDIYENLLEGESPLSKFKDVDVNHLSNVFQLFGYADERTGEIITNDPNFKVPT
GFDPRTRSWYLNAKKLNTFSLSEPYVDLITEKLMVTTSAPIYNKNDLTGVIFFDIPLDDV
QELIKSYNPFDAGTIFIVDNSGKIIFGNKNDISGKNLFGDFDSFPLSVSESKTKDKNGVN
YDVLIKMSDFGGWNLVSIIDHDKARSDIITLRNNSIFTAVILASVFFAILLFTMRLMLKP
LHQLTDAMVNISSGSADLTVRIPNSTDQEFSKIINSFNIFVGNLQSIVSEVKMNSEKINC
ITTETQELVEVCNNSVADQYRELDMLASSMNEMVATSNQIAQITSEASEITSKINGQVNE
GVGAVSSVTESVGNLVEKLDKTKSVIQDLNRQTQNIDVILKAINDIADQTNLLALNAAIE
AARAGENGRGFAVVADEVRSLAIKTQESTKNIGSIIHILQENSLLSVHVMDESFNIASET
MTISADSKQCLDNISQSVIQIVDITNQVATAAYEQSHVSEEINSNSISIKDKADTLSSLG
NKISQQAYSQKALIGHQDDLISKFII