Protein Info for CSW01_04160 in Vibrio cholerae E7946 ATCC 55056

Annotation: NAD(P)/FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 538 transmembrane" amino acids 100 to 120 (21 residues), see Phobius details PF21688: FAD-depend_C" amino acids 284 to 480 (197 residues), 278.7 bits, see alignment E=7.4e-87

Best Hits

KEGG orthology group: K07137, (no description) (inferred from 100% identity to vcj:VCD_003519)

Predicted SEED Role

"NAD(FAD)-utilizing dehydrogenase, sll0175 homolog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (538 amino acids)

>CSW01_04160 NAD(P)/FAD-dependent oxidoreductase (Vibrio cholerae E7946 ATCC 55056)
MIRLTELKLPLNHEEGALLDAIAAKLKIPAQQVLSFTLFRRGYDARKKSDIQLIYTVDVE
VANPEKLLAKFSKDQHVRPTPDMSYKFVAKAPENLPERPLVIGFGPCGLFAGLVLAQMGF
NPIIVERGKEVRERTKDTFGFWRKRTLNTESNVQFGEGGAGTFSDGKLYSQVKDPNFYGR
KVITEFVEAGAPEEILYVSKPHIGTFKLVTMIEKMRAKIIELGGEIRFSTRVDDIHMQDG
QITGVILSNGEEIQSRHVVLAVGHSARDTFEMLHARGVYMEAKPFSVGFRIEHKQSMIDE
ARFGPSAGHPILGAADYKLVHHCKNGRTVYSFCMCPGGTVVAATSEEGRVVTNGMSQYSR
AERNANSAIVVGISPEQDYPGDPLAGIRLQRELETNAYKLGGETYDAPAQKIGDFLKGRN
PSELGDVQPSFTPGIKLTDLSKALPAFAVEAIREAIPEFDRQIKGFASEDGLLTGVETRT
SSPVCIKRGKDFQSINLKGFYPAGEGAGYAGGILSAGIDGIKVAEAVARDMMARFAGE