Protein Info for CSW01_04095 in Vibrio cholerae E7946 ATCC 55056

Annotation: oxaloacetate decarboxylase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 transmembrane" amino acids 15 to 35 (21 residues), see Phobius details amino acids 43 to 63 (21 residues), see Phobius details amino acids 124 to 149 (26 residues), see Phobius details amino acids 160 to 184 (25 residues), see Phobius details amino acids 193 to 212 (20 residues), see Phobius details amino acids 219 to 238 (20 residues), see Phobius details amino acids 267 to 293 (27 residues), see Phobius details amino acids 313 to 331 (19 residues), see Phobius details amino acids 341 to 363 (23 residues), see Phobius details amino acids 410 to 431 (22 residues), see Phobius details TIGR01109: sodium ion-translocating decarboxylase, beta subunit" amino acids 19 to 426 (408 residues), 591.2 bits, see alignment E=3.4e-182 PF03977: OAD_beta" amino acids 20 to 430 (411 residues), 522.2 bits, see alignment E=3e-161

Best Hits

Swiss-Prot: 100% identical to OADB_VIBCH: Probable oxaloacetate decarboxylase beta chain (oadB) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K01572, oxaloacetate decarboxylase, beta subunit [EC: 4.1.1.3] (inferred from 100% identity to vco:VC0395_A0319)

Predicted SEED Role

"Oxaloacetate decarboxylase beta chain (EC 4.1.1.3)" in subsystem Na+ translocating decarboxylases and related biotin-dependent enzymes or Pyruvate metabolism I: anaplerotic reactions, PEP (EC 4.1.1.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.3

Use Curated BLAST to search for 4.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (433 amino acids)

>CSW01_04095 oxaloacetate decarboxylase subunit beta (Vibrio cholerae E7946 ATCC 55056)
MENILAMVRDFGLFHLQWGQGIMILVGLVLLYLAIVKRFEPLLLVPIGFGGILSNLPDAG
LAMSAIENAVYAAKPEVMTAFSEVLQLSSYMPADIKQALSSATPLQMTTLHLLAEQYQYS
DGMLYLFYSIAIASGAGPLIIFMGVGAMTDFGPLLANPKTLLLGAAAQFGIFTTVLGALA
LSSLGVMDFSVAQAAAIGIIGGADGPTAIYVSSMLAPELLGAIAVAAYSYMALVPMIQPP
IMRALTTQEERKIQMQQLRQVHKLEKIGFPLLLLILIALLLPSATPLLGMFCFGNLMREC
GVVERLSDTAQNALINIVTIFLGLSVGSKLMADKFLQPQTIGILVLGIVAFCVGTAAGVL
MAKLMNRFSTTKLNPLIGSAGVSAVPMAARVSNKVGLEANAQNFLLMHAMGPNVAGVIGS
AVAAGVMIKYVMG