Protein Info for CSW01_04035 in Vibrio cholerae E7946 ATCC 55056

Annotation: Fe(3+)-siderophore ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 transmembrane" amino acids 35 to 60 (26 residues), see Phobius details amino acids 88 to 108 (21 residues), see Phobius details amino acids 120 to 138 (19 residues), see Phobius details amino acids 143 to 163 (21 residues), see Phobius details amino acids 175 to 195 (21 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 263 to 291 (29 residues), see Phobius details amino acids 302 to 323 (22 residues), see Phobius details amino acids 330 to 352 (23 residues), see Phobius details PF01032: FecCD" amino acids 45 to 353 (309 residues), 245.6 bits, see alignment E=3.3e-77

Best Hits

Swiss-Prot: 43% identical to FEPG_ECOLI: Ferric enterobactin transport system permease protein FepG (fepG) from Escherichia coli (strain K12)

KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 100% identity to vco:VC0395_A0307)

MetaCyc: 43% identical to ferric enterobactin ABC transporter membrane subunit FepG (Escherichia coli K-12 substr. MG1655)
ABC-10-RXN [EC: 7.2.2.17]

Predicted SEED Role

"Ferric vibriobactin, enterobactin transport system, permease protein ViuG (TC 3.A.1.14.6)" in subsystem Iron acquisition in Vibrio (TC 3.A.1.14.6)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (358 amino acids)

>CSW01_04035 Fe(3+)-siderophore ABC transporter permease (Vibrio cholerae E7946 ATCC 55056)
METITSVAPEGRSNQTRFWLWRKGAYTLRVERRNIAVALVLSLIVLALMILATCVGKLPI
SISDVTAILLGEVTSGFKRQVLLDIRLPRIFTALFAGAALGLSGAIFQSISRNPLGSPDI
IGFTSGAATGALLQIILFSGSGVAVVFSAIAGGVMTAIAVYLLSVKSGTVGRYRLVLTGI
GVGSVLTALNGLLLVKGSLDSAITANLWLSGSLHAREWSHVFPVMCGVLVLLPLIKSLAR
SLQMLEMGDEIARQLGVVVEPIRLFMILAAVTLAALATGAAGPIAFIALAAPQLAARLRQ
TANIPLVSAGLMGACLLLGADLLTQWMPLALTLPIGRITGLVGGMYLLILLMRSKNTV