Protein Info for CSW01_03865 in Vibrio cholerae E7946 ATCC 55056

Annotation: protein translocase subunit SecF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 transmembrane" amino acids 20 to 37 (18 residues), see Phobius details amino acids 138 to 156 (19 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details amino acids 190 to 212 (23 residues), see Phobius details amino acids 238 to 257 (20 residues), see Phobius details amino acids 263 to 290 (28 residues), see Phobius details PF07549: Sec_GG" amino acids 35 to 60 (26 residues), 40.6 bits, see alignment (E = 1.3e-14) TIGR00966: protein-export membrane protein SecF" amino acids 39 to 285 (247 residues), 292.8 bits, see alignment E=2.6e-91 PF02355: SecD_SecF_C" amino acids 111 to 292 (182 residues), 240.8 bits, see alignment E=7.9e-76 TIGR00916: protein-export membrane protein, SecD/SecF family" amino acids 118 to 282 (165 residues), 191.9 bits, see alignment E=1.3e-60

Best Hits

Swiss-Prot: 88% identical to SECF_VIBAL: Protein translocase subunit SecF (secF) from Vibrio alginolyticus

KEGG orthology group: K03074, preprotein translocase subunit SecF (inferred from 100% identity to vcj:VCD_003582)

MetaCyc: 57% identical to Sec translocon accessory complex subunit SecF (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Protein-export membrane protein SecF (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (315 amino acids)

>CSW01_03865 protein translocase subunit SecF (Vibrio cholerae E7946 ATCC 55056)
MFQILKADKMIDFMRWSKFAFALSLVMIAASIFTLSTKWLNWGLDFTGGTLIEVGFEQPA
NLEQIRSALEAKGFGDATVQNFGSARDVMVRLRPRDDMAGEALGNQILAAIKEGTGGNVE
MRRIEFVGPNVGDELTEAGGLAILVSLLCILLYVSVRFEWRLAAGAVLALAHDVIITLGI
FSILQIEVDLTIVAALLTVVGYSLNDTIVVFDRIRENFRKMRKEEPAEIMNSSITQTLSR
TLITSGTTLFVVIALFTQGGAMIHGFALALLLGITVGTYSSIYVASALALKLGITREHLL
PPQVEKEGAELDEMP