Protein Info for CSW01_03085 in Vibrio cholerae E7946 ATCC 55056

Annotation: penicillin-binding protein activator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 601 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF04348: LppC" amino acids 39 to 599 (561 residues), 881.8 bits, see alignment E=1e-269

Best Hits

Swiss-Prot: 100% identical to LPOA_VIBC3: Penicillin-binding protein activator LpoA (lpoA) from Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)

KEGG orthology group: K07121, (no description) (inferred from 100% identity to vcm:VCM66_0539)

Predicted SEED Role

"LppC putative lipoprotein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (601 amino acids)

>CSW01_03085 penicillin-binding protein activator (Vibrio cholerae E7946 ATCC 55056)
MNHHQRRSVPRLLTPIALSIVLSACSTQPSSPDVVDITAQPLLTAQTYLMRADASQGNQQ
NDWLIMALKAAIEENNPDQAQLLIMRLAKQPLTPTQQAQWQLLRAQLLANTEQYQEALEQ
LSFQANWSLPQVQWQQYHQLRADIFTALDRSFDSTRELVALYGLSSNKDKEALADQIWAN
LNHYSASKIIKLSTEPDEAQLDGWLQLAIYMKTLGSDLPQLKNTLEKWLAENPQHPAAIY
TPKAITDILALEIVKPTNTALLLPLTGKFAKQAQFIRDGFVFAMMNDADRQTNATLTIID
TNAETLESVDAILTSKQIDFVVGPLIKGNIEKLQQFQQSRGQMIPTLALNIPDQIDTTAG
ACYLALSPEQEVAQAAKHLFTQGYRYPLILAPQNAYGERVVEAFNEEWRRYSKNKVAVNL
FGDKRQLQRNINSIFGLQDSQQNIAQMESLLGMGLESQPRSRRDIDAVYIVANSSELTLI
KPFIEVAINPDTRPPKLFSNSNSNTGGRQYEDLSGVTYSDIPLLIQPAPSIKEQLTQIWP
ESSNAERRLQALGMDAYRLMVELPQMKIVEGYTIDGQTGVLSIDEQCVVQREISWAEHGV
R