Protein Info for CSW01_02190 in Vibrio cholerae E7946 ATCC 55056

Annotation: rod shape-determining protein MreC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details TIGR00219: rod shape-determining protein MreC" amino acids 1 to 273 (273 residues), 277.3 bits, see alignment E=6.4e-87 PF04085: MreC" amino acids 123 to 270 (148 residues), 153.7 bits, see alignment E=1.5e-49

Best Hits

Swiss-Prot: 45% identical to MREC_HAEIN: Cell shape-determining protein MreC (mreC) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03570, rod shape-determining protein MreC (inferred from 100% identity to vch:VC0416)

Predicted SEED Role

"Rod shape-determining protein MreC" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (296 amino acids)

>CSW01_02190 rod shape-determining protein MreC (Vibrio cholerae E7946 ATCC 55056)
MKPIFGRGPSLQLRLFFAVMLSASLMLADSRLGAFSHVRFLLNSLVAPIQYAADLPRVLF
DDFYDSISSHQQLRENNQLLKREVLTLKSNLLLLEQYKEENQRLRKLLGSSFLRDEKKVV
TEVMAVDTSPYRHQVVIDKGRVDGVYEGQPIINEKGIVGQVTFVAAHNSRVLLLIDPNTA
IPVQNIRNDIRVIASGNGQTDQIQLEHIPTSTDIEVGDMLVTSGLGGVYPEGYPVAIVSQ
VDKDTRREFASIKADPVVEFDRLRYLLLIWPNEDRLQKVMQADPQVLLEEEANAQQ