Protein Info for CSW01_01325 in Vibrio cholerae E7946 ATCC 55056
Annotation: acetyltransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
Swiss-Prot: 52% identical to VIOB_ECOLX: dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase (vioB) from Escherichia coli
KEGG orthology group: K00633, galactoside O-acetyltransferase [EC: 2.3.1.18] (inferred from 100% identity to vco:VC0395_A2632)MetaCyc: 52% identical to dTDP-4-amino-4,6-dideoxy-D-glucose acetyltransferase (Escherichia coli O7:K1)
RXN-13755 [EC: 2.3.1.209]
Predicted SEED Role
"Galactoside O-acetyltransferase (EC 2.3.1.18)" in subsystem Lactose utilization (EC 2.3.1.18)
MetaCyc Pathways
- dTDP-N-acetylviosamine biosynthesis (1/4 steps found)
- superpathway of dTDP-glucose-derived O-antigen building blocks biosynthesis (2/19 steps found)
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.3.1.18 or 2.3.1.209
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (188 amino acids)
>CSW01_01325 acetyltransferase (Vibrio cholerae E7946 ATCC 55056) MSGNGYYSEDVLKQMGFSSLGKNVKISEKASLYGISRISIGSNVRIDDYVTISAGVGGVE IGSHVHIGVYSSLIGAGKITLEDFVGVSGRVSIYSSSDDYTGMAMSNPTVPEELTKVTSL PVLIKKHSILGAGCVVLPKVIVGEGVSVGALSLVNKSLDDWHIYSGNPIQKFIRKARKPL ELEKKLIL