Protein Info for CSW01_01100 in Vibrio cholerae E7946 ATCC 55056

Annotation: PTS N-acetylmuramic acid EIIBC component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 481 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 124 to 153 (30 residues), see Phobius details amino acids 165 to 186 (22 residues), see Phobius details amino acids 191 to 210 (20 residues), see Phobius details amino acids 225 to 249 (25 residues), see Phobius details amino acids 262 to 286 (25 residues), see Phobius details amino acids 305 to 331 (27 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details amino acids 374 to 394 (21 residues), see Phobius details amino acids 401 to 423 (23 residues), see Phobius details amino acids 448 to 473 (26 residues), see Phobius details PF00367: PTS_EIIB" amino acids 11 to 43 (33 residues), 40.5 bits, see alignment (E = 1.4e-14) PF02378: PTS_EIIC" amino acids 127 to 408 (282 residues), 123.7 bits, see alignment E=8.6e-40

Best Hits

Swiss-Prot: 100% identical to PTYBC_VIBCH: PTS system N-acetylmuramic acid-specific EIIBC component (murP) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K11191, PTS system, N-acetylmuramic acid-specific IIB component [EC: 2.7.1.69] K11192, PTS system, N-acetylmuramic acid-specific IIC component (inferred from 100% identity to vco:VC0395_A2586)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (481 amino acids)

>CSW01_01100 PTS N-acetylmuramic acid EIIBC component (Vibrio cholerae E7946 ATCC 55056)
MAKITQTMMAQVLSLVGGSGNVAKCGNCMTRLRLTLNNSALADHAALKKISGVMGVVESD
AQLQIILGPGKAQTAADMMNALIESGDNVAPAVSEADLSTIAAQQKKQMKSKQTSAVQRF
LSKFATIFTPLIPGFIAAGLLLGIATLLEQIYVVGQTPSEFMLDLVAYLKVFGKGLFAFL
SILIGYNAQQAFGGSGVNGAILASLFVLGYDPEATKGIYSGMSEFFGFAIDPRGNIIGVL
LAAILGAQVERKVREYMPDDLDMILTSVVTLLIMGAVTFLIIMPIGGELFKGMSWLFLNL
NDNPLGAAILAGLFLISVVFGIHQGFVPVYFALMEAQGFNSLFPILAMAGAGQVGASLAL
YARAKKETTIRTQIKGAIIPGILGIGEPLIYGVTLPRVKPFVTACIGGAAGGFFIGLISY
LGLPVGLNTVFGPSGVVAIPLMTSADGIFAGMAVFVGGLLISYTVGFAATYFFGCKDVDL
S