Protein Info for CSW01_01080 in Vibrio cholerae E7946 ATCC 55056

Annotation: Fe(3+)-hydroxamate ABC transporter permease FhuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 653 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 55 to 75 (21 residues), see Phobius details amino acids 87 to 107 (21 residues), see Phobius details amino acids 113 to 134 (22 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 188 to 210 (23 residues), see Phobius details amino acids 219 to 239 (21 residues), see Phobius details amino acids 245 to 262 (18 residues), see Phobius details amino acids 274 to 297 (24 residues), see Phobius details amino acids 303 to 321 (19 residues), see Phobius details amino acids 345 to 364 (20 residues), see Phobius details amino acids 385 to 404 (20 residues), see Phobius details amino acids 416 to 435 (20 residues), see Phobius details amino acids 441 to 460 (20 residues), see Phobius details amino acids 471 to 490 (20 residues), see Phobius details amino acids 516 to 538 (23 residues), see Phobius details amino acids 558 to 586 (29 residues), see Phobius details amino acids 598 to 619 (22 residues), see Phobius details amino acids 623 to 648 (26 residues), see Phobius details PF01032: FecCD" amino acids 12 to 323 (312 residues), 216.8 bits, see alignment E=2e-68 amino acids 372 to 648 (277 residues), 222.5 bits, see alignment E=3.4e-70

Best Hits

KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 100% identity to vch:VC0203)

Predicted SEED Role

"Ferrichrome transport system permease protein FhuB (TC 3.A.1.14.3)" in subsystem Iron acquisition in Vibrio (TC 3.A.1.14.3)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (653 amino acids)

>CSW01_01080 Fe(3+)-hydroxamate ABC transporter permease FhuB (Vibrio cholerae E7946 ATCC 55056)
MSVLRLTGLGALTLLLALVSLQWGHNLTLNEQWQLVLGHQAAQSFAQVNFIYAQLPRAVM
AIVVGAVLGLVGSLMQQLTQNRLTSPLTLGTSSGAWLGLIIVNIWFSDWVADYSALAAMA
GALLAFALIISIAGLRNLTGLPLVVSGMVVNILLGSIATALVLLNEEFAQNVFMWGAGDL
AQNGWEWLTWLLPRLALVFPLLLFAPRVLTLLRLGHEGAAARGLAVLPAFLFLMAGGIWL
VSASITAVGVIGFIGLLTPNIARSLGARTTKMELYSSALLGALLLLATDMLAMGLSVWAE
EVVPSGITAAVIGAPALIWFSRRQLQAQDSLSISLSSHRRSPSRWAVMLIAAALLLALSL
HIGWQMESASWALPSEFQWPLRWPRMLTALFAGVGLAIAGTLLQRLIYNPLASPDILGVS
SGATFALVFASLFLGQSLQSTHWMTALLGSAAVLVALLLLGRRHHYAPSSLILTGIAITA
LLEALVQFTLAKGTGDSYQILLWLSGSTYRATGEQALLLSVGVVGLTLLALGLSRWLTLI
SIGRGFASARGLSASRASLVLLILVALLCALVTATMGPVSFVGLIAPHMAMMLGAQRAPS
QLLLAALVGGTLMLWADWLGQALLFPAQIAAGTLVAIIGGSYFLLLLLSQRAR