Protein Info for CSW01_01010 in Vibrio cholerae E7946 ATCC 55056

Annotation: oligopeptidase A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 680 PF19310: TOP_N" amino acids 30 to 145 (116 residues), 98.2 bits, see alignment E=3e-32 PF01432: Peptidase_M3" amino acids 222 to 677 (456 residues), 555.9 bits, see alignment E=1.1e-170

Best Hits

Swiss-Prot: 71% identical to OPDA_SALTY: Oligopeptidase A (prlC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01414, oligopeptidase A [EC: 3.4.24.70] (inferred from 100% identity to vcj:VCD_001425)

MetaCyc: 71% identical to oligopeptidase A (Escherichia coli K-12 substr. MG1655)
Oligopeptidase A. [EC: 3.4.24.70]

Predicted SEED Role

"Oligopeptidase A (EC 3.4.24.70)" in subsystem Protein degradation (EC 3.4.24.70)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.70

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (680 amino acids)

>CSW01_01010 oligopeptidase A (Vibrio cholerae E7946 ATCC 55056)
MSNPLLTFTDLPPFSAIKPEHVKPAVEQAIADCRHTIDKVLAENPQPSWESVIAPIEEVD
DRLSRIWSPVSHMNSVVNSDELREAYESCLPLLSEYSTWVGQHKGLFEAYKTIKESAEFA
KLDRAQQKNISDSLRDFELSGIGLPLQEQKRYGEISKRMSELGSKFSNNVLDATMGWTKQ
ITDVNLLAGMPESALAAAQAAAEAKGLEGYLLTLDIPSYLPVMTYCDNQALRKEVYEAYV
TRASDRGPNAGKWDNSEIIAEQLKLRHEIARMLGFSTYSEKSLATKMAQTTDQVLGFLND
LANKAKPQGEREVEELRQFAESEFGVKQLELWDIAYYSEKQKQHLFEISDEELRPYFPEQ
KVVNGLFEVLSRLFGMQVKERQGVDVWHESVRFFDIFDAQGTLRGSFYLDLYAREHKRGG
AWMDECRVRRTTDSGALQTPVAYLTCNFNRPVGDKPALFTHDEVTTLFHEFGHGIHHMLT
QVEVGAVSGINGVPWDAVELPSQFLENWCWQEEALAFISGHYQTGEPLPKAMLDKMLAAK
NFQSAMFILRQLEFGLFDFTLHTTYDPEVGPKVLETLAEVKKKVAVLPGLEWNRFSHSFS
HIFAGGYSAGYYSYLWAEVLSADAFSRFEEEGIFNRETGQSFLNNILEMGGSEEPMELFK
RFRGREPQIDALLRHAGIAA