Protein Info for CSW01_00535 in Vibrio cholerae E7946 ATCC 55056

Annotation: thiosulfate sulfurtransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00581: Rhodanese
  • amino acids 10 to 98 (89 residues), 65.3 bits, E=3e-22

Best Hits

Swiss-Prot: 100% identical to GLPE_VIBCM: Thiosulfate sulfurtransferase GlpE (glpE) from Vibrio cholerae serotype O1 (strain M66-2)

KEGG orthology group: K02439, thiosulfate sulfurtransferase [EC: 2.8.1.1] (inferred from 100% identity to vch:VC0100)

MetaCyc: 59% identical to thiosulfate sulfurtransferase GlpE (Escherichia coli K-12 substr. MG1655)
Thiosulfate sulfurtransferase. [EC: 2.8.1.1]; 2.8.1.- [EC: 2.8.1.1]

Predicted SEED Role

"Thiosulfate sulfurtransferase GlpE (EC 2.8.1.1)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (EC 2.8.1.1)

MetaCyc Pathways

• thiosulfate disproportionation IV (rhodanese) (1/1 steps found)
• sulfide oxidation IV (mitochondria) (2/5 steps found)

Isozymes

Compare fitness of predicted isozymes for: 2.8.1.1

Use Curated BLAST to search for 2.8.1.1

Protein Sequence (106 amino acids)

>CSW01_00535 thiosulfate sulfurtransferase (Vibrio cholerae E7946 ATCC 55056)
MDHFLHIDVNAAQAMMEQKQAHLVDIRDPQSFQLAHAKNAYHLTNQSMVQFMEQAEFDQP
VLVMCYHGISSQGAAQYLVNQGFEEVYSVDGGFEAWHRANLPIEAS