Protein Info for CSW01_00470 in Vibrio cholerae E7946 ATCC 55056

Annotation: twin-arginine translocase subunit TatC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 76 to 96 (21 residues), see Phobius details amino acids 117 to 139 (23 residues), see Phobius details amino acids 158 to 183 (26 residues), see Phobius details amino acids 195 to 211 (17 residues), see Phobius details amino acids 217 to 237 (21 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 10 to 227 (218 residues), 251.1 bits, see alignment E=5.3e-79 PF00902: TatC" amino acids 12 to 222 (211 residues), 241.4 bits, see alignment E=4.3e-76

Best Hits

Swiss-Prot: 70% identical to TATC_HAEIN: Sec-independent protein translocase protein TatC (tatC) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 100% identity to vco:VC0395_A2427)

MetaCyc: 67% identical to twin arginine protein translocation system - TatC protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (250 amino acids)

>CSW01_00470 twin-arginine translocase subunit TatC (Vibrio cholerae E7946 ATCC 55056)
MSSVEQTQPLISHLLELRNRLLKAVAAVVVIFIGLIYFSNEIYEFVSKPLVERLPAGATM
IATDVASPFFTPLKLTLIAAVFLAVPFILYQVWAFVAPGLYKHERRLIFPLLVSSSLLFY
CGVAFAYFVVFPLVFGFFTAISLGGVEFATDIASYLDFVLALFLAFGIAFEVPVAIILLC
WTGATTPKSLSEKRPYIIVGAFVVGMLLTPPDMISQTLLAIPMCLLFEVGLFFARFYTRD
EADEGQEEEE