Protein Info for CSW01_00365 in Vibrio cholerae E7946 ATCC 55056

Annotation: aminopeptidase P family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 597 transmembrane" amino acids 46 to 68 (23 residues), see Phobius details PF01321: Creatinase_N" amino acids 8 to 138 (131 residues), 59.5 bits, see alignment E=1e-19 PF16189: Creatinase_N_2" amino acids 148 to 306 (159 residues), 126.6 bits, see alignment E=2e-40 PF00557: Peptidase_M24" amino acids 309 to 525 (217 residues), 180.2 bits, see alignment E=9.1e-57 PF16188: Peptidase_M24_C" amino acids 534 to 594 (61 residues), 82.6 bits, see alignment E=3.1e-27

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 100% identity to vcm:VCM66_0067)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (597 amino acids)

>CSW01_00365 aminopeptidase P family protein (Vibrio cholerae E7946 ATCC 55056)
MSNLHSQRLADFRHWLHTQQLDAFIVPHEDEYLGEYVPEHNERLHWLTGFTGSAGAAIVT
LSGAAIFVDGRYTVQVRKQVSSELFEYCHLIEQPYLNWLVTQLPAGAKVGYDPRMHRGSW
LTQAQKQLAGKINLCAVSSNPIDLLWQDRPVPAASEMRLIPLDRVGQSSLEKRQSIASTL
RDKNADCVVLTELDSIAWLLNIRGLDVSRLPVLLSHAIVHNDSSVDFFFDPARLATDFDA
HVAGTVRVHHPDQLEAQLHQLSGRRVMLDSATSNAWFTLTLQNAGAELLNEADPCLLPKA
AKNNTEIAGMRACHIRDGAAMVQFLAWLDNEVANGRLHNEAELADRLEAFRRQDPTLVDL
SFDTISAAGTNAAMCHYNHQNQPEPGQLSMDSLYLVDSGGQYLDGTTDITRTVAIGQVSA
EMKQQFTLVLKGHIALARARFPKGTTGSQLDVLARQHLWAQGYDYDHGTGHGVGHFLSVH
EGPQRIAKVHNSVALRPGMVLSNEPGYYRADAFGIRIENLELVTEFATQGDFSVLGFESL
TRCPIDKRAIEVNLLTKPELHWLNQYHQKVWDEVSPLIKEAHVREWLQQATSPLSHV