Protein Info for CCNA_03858 in Caulobacter crescentus NA1000

Annotation: protein translocase subunit secB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 163 PF02556: SecB" amino acids 17 to 154 (138 residues), 160.3 bits, see alignment E=1.4e-51 TIGR00809: protein-export chaperone SecB" amino acids 18 to 153 (136 residues), 124.8 bits, see alignment E=1.3e-40

Best Hits

Swiss-Prot: 100% identical to SECB_CAUVC: Protein-export protein SecB (secB) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K03071, preprotein translocase subunit SecB (inferred from 100% identity to ccs:CCNA_03858)

Predicted SEED Role

"Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8GW20 at UniProt or InterPro

Protein Sequence (163 amino acids)

>CCNA_03858 protein translocase subunit secB (Caulobacter crescentus NA1000)
MTDTIAPEATPEGAEAGQAGIRILAQFVRDFSFENPLAPDALRAGAAQPAIDMGVEMNAR
GRADGLFEVDLKLSARAEREGQAVFHVEVVYGGLFHIAGIAEEDLEPVLLIECPRFLFPY
ARRLISDVTAEGGFPPFLIDPIDFAGVYAARKAQAEGQQVGNA