Protein Info for CCNA_03640 in Caulobacter crescentus NA1000

Annotation: phenylpropionate dioxygenase ferredoxin reductase subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 412 PF07992: Pyr_redox_2" amino acids 11 to 308 (298 residues), 233.7 bits, see alignment E=9.4e-73 PF00070: Pyr_redox" amino acids 152 to 233 (82 residues), 60.7 bits, see alignment E=4.7e-20 PF14759: Reductase_C" amino acids 327 to 410 (84 residues), 113.3 bits, see alignment E=1.9e-36

Best Hits

Swiss-Prot: 44% identical to THCD_RHOER: Rhodocoxin reductase (thcD) from Rhodococcus erythropolis

KEGG orthology group: K00529, ferredoxin--NAD+ reductase [EC: 1.18.1.3] (inferred from 100% identity to ccs:CCNA_03640)

MetaCyc: 44% identical to diphenylamine dioxygenase ferredoxin reductase component (Burkholderia sp. JS667)
RXN-11506

Predicted SEED Role

"Ferredoxin reductase" in subsystem Anaerobic respiratory reductases

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.18.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CFH7 at UniProt or InterPro

Protein Sequence (412 amino acids)

>CCNA_03640 phenylpropionate dioxygenase ferredoxin reductase subunit (Caulobacter crescentus NA1000)
MSAEVNQNACVVIVGAGHAGGSVAAFLRQYGHEGRIVLIGDEPLLPYQRPPLSKAWLKGE
ADADSLSLKPAGWYADNNVMLRLGGVAERINRSDKTVALASGEVIPYDFLVLATGARARE
LPIPGADLAGVLALRTAADAELLKNALGPDKRLAVVGGGYVGLEAAASARALGSHAMVIE
RESRVLARVACETLSHFFQDYHGKHGVAFELNAGVAAFEGHDGHVTGVRFNDGRVVACDV
ALVGVGAVPNDELAKDAGLSTANGVVVDLEARTDDPSIFAIGDVTHRPLPLYDRQFRLES
VPNALEQAKQAASAILGRPGPAPETPWFWSDQYDLKLQIAGLPFDADRQVVRGDVAAAKF
AVFHLKGDLVQAVEAVNAPPEFMAGKQLIAKRTPVDANKLADPSVSMKEVAA