Protein Info for CCNA_03591 in Caulobacter crescentus NA1000

Annotation: anti-anti sigma factor/receiver protein PhyR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 PF00072: Response_reg" amino acids 143 to 251 (109 residues), 48 bits, see alignment E=6.7e-17

Best Hits

Swiss-Prot: 54% identical to PHYR_METEA: Phyllosphere-induced regulator PhyR (phyR) from Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1)

KEGG orthology group: None (inferred from 100% identity to ccr:CC_3477)

Predicted SEED Role

"DNA-directed RNA polymerase specialized sigma subunit, sigma24-like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CBZ6 at UniProt or InterPro

Protein Sequence (266 amino acids)

>CCNA_03591 anti-anti sigma factor/receiver protein PhyR (Caulobacter crescentus NA1000)
MSLLARLAPHLPYIRRYARALTGDQATGDHYVRVALEALAAGELVLDANLSPRVALYRVF
HAIWLSSGAQLEVGHDQGLHAGDDAAQRLMRIAPRSRQAFLLTALEGFTPTEAAQILDCD
FGEVERLIGDAQAEIDAELATEVLIIEDEPVIAADIEALVRELGHDVTDIAATRGEALEA
VTRRTPGLVLADIQLADGSSGIDAVKDILGRMDVPVIFITAFPERLLTGERPEPTFLITK
PFQPETVKAAIGQALFFHPRRTAKAA