Protein Info for CCNA_03548 in Caulobacter crescentus NA1000

Annotation: carboxy-terminal processing protease precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR00225: C-terminal processing peptidase" amino acids 53 to 371 (319 residues), 323.3 bits, see alignment E=8.2e-101 PF00595: PDZ" amino acids 97 to 166 (70 residues), 48.8 bits, see alignment E=1.5e-16 PF13180: PDZ_2" amino acids 99 to 171 (73 residues), 43.8 bits, see alignment E=5.3e-15 PF17820: PDZ_6" amino acids 116 to 168 (53 residues), 52.9 bits, see alignment 5.3e-18 PF03572: Peptidase_S41" amino acids 195 to 362 (168 residues), 189.6 bits, see alignment E=6.4e-60

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 100% identity to ccs:CCNA_03548)

Predicted SEED Role

"Carboxyl-terminal protease (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CF90 at UniProt or InterPro

Protein Sequence (464 amino acids)

>CCNA_03548 carboxy-terminal processing protease precursor (Caulobacter crescentus NA1000)
MRKYLLIGVSAFVLGAGTMAYISPIAQANNAPKAQTYKLLELFGDVLGTVEDQYVTEVDD
KKLIEAALDGMLTSLDPHSGYLAPDAFEDMQDTTRGEYGGLGLEVTSEEGVVKVISPMDG
TPASRAGIQAGDYITAVNGQSVLGLTVNEAVKQMRGTAGEAVTLTIAREKTDPFDVKLVR
EVIKPKAAIARMEGDYGYVRLPGFNEKATDALASSVSELKSKNPKMKGLILDLRNNPGGL
LDQAVGVADVFLDGGEVVSQRGRDPRNIQRYNARGGDMLNGLPMVVLINQGSASAAEIVA
GALQDRKRAEVVGLTSFGKGSVQTVIPLRGGADGALKLTTARYFTPSGRSIQKTGIAPDL
EVAQTRDQAQDIANRVWFSEASFKNALNADEGKSRVGAHTPAEAPPTGFDDKKGDFQLQR
AIAVLQAGGVAKTPKLPKPAAKVAEVTAKAAAAAGGKTPVTEVK