Protein Info for CCNA_03522 in Caulobacter crescentus NA1000

Annotation: Zn-dependent protease TldD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 478 PF01523: PmbA_TldD_1st" amino acids 38 to 97 (60 residues), 42.1 bits, see alignment E=1.2e-14 PF19290: PmbA_TldD_2nd" amino acids 125 to 234 (110 residues), 66.1 bits, see alignment E=5.8e-22 PF19289: PmbA_TldD_3rd" amino acids 242 to 475 (234 residues), 228 bits, see alignment E=1.2e-71

Best Hits

KEGG orthology group: K03568, TldD protein (inferred from 100% identity to ccs:CCNA_03522)

Predicted SEED Role

"TldD protein, part of TldE/TldD proteolytic complex"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CDI5 at UniProt or InterPro

Protein Sequence (478 amino acids)

>CCNA_03522 Zn-dependent protease TldD (Caulobacter crescentus NA1000)
MNAPIPASSLSILDAAGVDPDRARAILGEALAGADDGELFLERSESEAFVFDDGRLKSAS
YDSGEGFGLRVVAGETAGYAHAAEISEAAIRRASDSASLAKRGHAGVSAEGPRATNEKLY
GEDNPVSAPDFSDKVALLQEIDAFARARDPRVVQVMASMAGERRVVEILRADGRLIRDVR
PLVRVNVQVTVEKDGRRESGSSGAGGRAGFAAWISPDKWQDQVDEALRMALVNLDAVACP
AGEMDVVLGPGWNGVLLHEAVGHGLEGDFNRKGISAFSGRIGERVAAPGVTVFDDGSIPG
RRGSLTVDDEGTPTERTILIEDGILVGYMHDRMSARLMGMKATGNGRRQSYAHMPMPRMT
NTGMLAGEHDPQEMIASLKRGLYCANFGGGQVDITNGKFVFQCTEAYLVEDGKITAPVKG
ATLIGDGPSALTRVTMIGNDFDFDPGIGVCGKSGQGVPVGVGQPSLKITGLTVGGTAV