Protein Info for CCNA_03504 in Caulobacter crescentus NA1000

Annotation: acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 603 PF02771: Acyl-CoA_dh_N" amino acids 91 to 172 (82 residues), 48.4 bits, see alignment E=2.9e-16 PF02770: Acyl-CoA_dh_M" amino acids 177 to 285 (109 residues), 52.4 bits, see alignment E=1.2e-17 PF00441: Acyl-CoA_dh_1" amino acids 296 to 460 (165 residues), 80.9 bits, see alignment E=2.8e-26 PF08028: Acyl-CoA_dh_2" amino acids 314 to 454 (141 residues), 25 bits, see alignment E=5.1e-09 PF12806: Acyl-CoA_dh_C" amino acids 477 to 596 (120 residues), 74.3 bits, see alignment E=2.5e-24

Best Hits

KEGG orthology group: K00257, [EC: 1.3.99.-] (inferred from 100% identity to ccr:CC_3393)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7, 1.3.99.-

Use Curated BLAST to search for 1.3.8.7 or 1.3.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CCF5 at UniProt or InterPro

Protein Sequence (603 amino acids)

>CCNA_03504 acyl-CoA dehydrogenase (Caulobacter crescentus NA1000)
MATLGAPLKDGARPGVSPMTFRAPVRDLAFSLRHVAGFERLADAFPEADADTVAAVLEAA
GAFASDILAPLNRQGDLVGARLENGVVRTAPGFADAYQQFAQGGWTSLAAPAEHGGQGLP
KTLEVAVLEMVQAANMAFGLCPMLSLGAIEALELCGSPEQKAKYLGKLVSGEWTGTMNLT
EPQAGSDLAALTTMATPDGDGGWRITGQKIYITWGDHDAADNIVHLVLARTPDAPPGVKG
ISLFLAPKVLVGDDGKLGPANALRAGSLEHKLGIHGSPTCVMLFEGAKAELVGGLGQGLP
NMFVMMNAARLQVGTQGVAIAERAYQQALAFSQDRAQGRSAWTGAYPSRLFDHPDVRRTL
VLMKAHIEAARGICLSTAVAADLARAAPDAATRTAAKLREELLTPIAKAWSTDIGVWVAS
QGVQIHGGMGFIEETGAAQHYRDARIAPIYEGTNGIQAIDLVGRKLMLGEGQAVGDLMDD
IRDTIDLLKASDLKSVGLRLEAALDAAASATAWLIERRAKAMPDALAGATAYQTLLGDVV
GGWMLAKGALAADGEADAAWAESKRALARVFAEAVLAQVPGAAAGVMIGAADFEAMTPEV
LGA