Protein Info for CCNA_03491 in Caulobacter crescentus NA1000

Annotation: gluconate 5-dehydrogenase (Ga5DH)-related protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 PF00106: adh_short" amino acids 11 to 205 (195 residues), 158.8 bits, see alignment E=1.8e-50 PF08659: KR" amino acids 13 to 172 (160 residues), 57.8 bits, see alignment E=2.2e-19 PF13561: adh_short_C2" amino acids 19 to 258 (240 residues), 199.6 bits, see alignment E=9.1e-63

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_3380)

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CF30 at UniProt or InterPro

Protein Sequence (260 amino acids)

>CCNA_03491 gluconate 5-dehydrogenase (Ga5DH)-related protein (Caulobacter crescentus NA1000)
MAYAPFNLSGKVALVTGGNRGIGLGMAKAMAQAGADIVIWGSNPERNLAAEQTLTALGVR
VKAQTVDVSDEAQVREGMEEAVAAMGRVDSVFANAGIGYGSPSFVDMSTEVYRKVLAVNL
DGVFFTLREACRHMVERAKAGDPGGSLVGVASLAAIEGAARNEAYAATKGAVISMIKSVA
VEHARYGVRANAILPGWIATDMTAGAQGNAAFAEKVIPRVPARRWGEPEDFGGMAVYLAS
DASSYHSGTTLVIDGGYSIF