Protein Info for CCNA_03467 in Caulobacter crescentus NA1000

Annotation: zinc-dependent metalloprotease, MMP subfamily 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 834 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF17148: DUF5117" amino acids 101 to 289 (189 residues), 100.2 bits, see alignment E=1.3e-32 PF16313: DUF4953" amino acids 418 to 722 (305 residues), 211.3 bits, see alignment E=2e-66

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_03467)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CF07 at UniProt or InterPro

Protein Sequence (834 amino acids)

>CCNA_03467 zinc-dependent metalloprotease, MMP subfamily 2 (Caulobacter crescentus NA1000)
MGKTFIKSLMAGACALAMAGSAVAADKSPAKPVDKFAEAIAGLERKDGLVPVFVDKKDGK
VLLLLPKPGADGIAGRYLYQTYLRAGLGSNPTGLDRSAPGDTQIIAFRKVGGKVVAQFEN
WGFSAARGSADEQKAVAESFPVSTVWSNVIEAERADGGLLVDVTSFLTRDAQGIAKTLKR
SRQGDFRLHDGLSYADTGAVNAFPKNIELEAVQTFVGDEPGSEVRGIVPDPRNVTLVLHH
SLVALPEPGYQPRQNDPRVGVIDHTVADYSAPLNEPIVHRLVHRFRLEKTDPTAARSPVK
TPIVFYIDRAAPEPVRSALMDGARWWAEAFDAAGFIDAFKVEVLPEGVSPLDARYSVVNW
VHRQTRGWSYGHAVVDPRTGEIVKGDVLLGSQRIRQDRLIFEGLAGSDATGKGGPNDPIE
ISLARLRQLATHEIGHSIGLQHNFAASAYGGRASVMDYPAPKIALKDGKLDFTDAYGRGV
GDWDKFAIDWLYGPAPAGADEKAWLKAKADRSQAAGLRYVSDEDGRSADTAHPLGAVWDN
GSDPVAELDHLMAVRKVALDRFGLGNLPKGASVADLRRVIVPIYIFHRYQIDATAKLVGG
IDFTYAAEGDGHEASKVVPVARQAAAVDALLRTLSPAALDLSDKTLDVLNAGQSQGNDKA
YDIETFGQGPVFDLPAASEVAADLVWSALFAPARLNRLVEAKRRDPGQLGLEGVMDKALA
AVAFDGKATGRQAELARRVRQRLVVSLAQTLNDKTLAPTAAAVIRARLVDWGKGLAKAGG
DSADRAQARLLAGIVADETGGRLAALVEGGKAKVDIPPGPPIGETDWFGDILAD