Protein Info for CCNA_03383 in Caulobacter crescentus NA1000

Annotation: multidrug/protein/lipid ABC transporter family, ATP-binding and permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 617 transmembrane" amino acids 56 to 77 (22 residues), see Phobius details amino acids 96 to 117 (22 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details amino acids 196 to 214 (19 residues), see Phobius details amino acids 279 to 300 (22 residues), see Phobius details amino acids 312 to 334 (23 residues), see Phobius details TIGR02204: ABC transporter, permease/ATP-binding protein" amino acids 37 to 612 (576 residues), 918.3 bits, see alignment E=1e-280 PF00664: ABC_membrane" amino acids 58 to 321 (264 residues), 163.3 bits, see alignment E=1e-51 PF00005: ABC_tran" amino acids 392 to 541 (150 residues), 117.1 bits, see alignment E=9.6e-38

Best Hits

Swiss-Prot: 37% identical to MSBA_DESPS: Lipid A export ATP-binding/permease protein MsbA (msbA) from Desulfotalea psychrophila (strain LSv54 / DSM 12343)

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 100% identity to ccr:CC_3274)

Predicted SEED Role

"ABC-type multidrug transport system, ATPase and permease components"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CD50 at UniProt or InterPro

Protein Sequence (617 amino acids)

>CCNA_03383 multidrug/protein/lipid ABC transporter family, ATP-binding and permease protein (Caulobacter crescentus NA1000)
MMTDANSGDQKVEGRPGAGAELVQGMTEAGARRPRRKDIRPLAHLLPFVIAHKGDGLAAG
FFLLFSTAATLGLTYAFKNVIDHGFSKGQDAAINSAFVGLGAVALVLALATALRFFFITR
LGERVVADLRRKLYGHTLSLDQPYFLKTRTGEVLSRLTTDVALVEQLVGASISIALRNIL
NLIGGLTAMAVVSPKLAGFIVLMVPVILAPMFLVGRRVRKLTVTAQDRFADAVGYAGESL
DALETVQAFGRESASSGRFGAAVEAAYKASVRRITTRATMTAMVITLAFGGITLLLWTGA
RLVLAGEMTGGTLAQFAMLAVMAAGSIGALGEVWGDVQKASGAMDRISELLNAKPDIAAP
PQPKTLPVPGQGEIAFENVVFAYPGRPDLPALNGFDLRVKPGETVALVGPSGAGKSTVLR
LLLRFYDPQSGCILLDGVNLRDAEPAEVRARMALVAQDSPLFSGSAMDNIRFGRPDATDE
QVRAAADAAQATGFLSALPEGFDTPVGERAKTLSGGQRQRLAIARALVREAPILLLDEAT
SALDAESEQLVQQALATAMEGRTTLVIAHRLATVLKADRIVVMEEGRVVEQGAHAELFAK
GGLYARLARLQFGVEAA