Protein Info for CCNA_03347 in Caulobacter crescentus NA1000

Annotation: N-acyl-L-amino acid amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF04389: Peptidase_M28" amino acids 90 to 202 (113 residues), 25.1 bits, see alignment E=2e-09 PF01546: Peptidase_M20" amino acids 106 to 468 (363 residues), 114.9 bits, see alignment E=7.3e-37 PF07687: M20_dimer" amino acids 224 to 370 (147 residues), 56.2 bits, see alignment E=4.7e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_3239)

Predicted SEED Role

"Peptidase M20:Peptidase dimerisation"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CEN1 at UniProt or InterPro

Protein Sequence (474 amino acids)

>CCNA_03347 N-acyl-L-amino acid amidohydrolase (Caulobacter crescentus NA1000)
MKPMAWMTAGALIALATAANAQTAEPPKTVRPDQLAFRDLYKELVEINTTLSVGSCTAAS
EAMGARLKAAGFPEADVRVVVEPKHPREGNLVAVLRGTDATTKPMLLLAHIDVVEAKRED
WTRDPFKLVEENGYFYGRGTSDDKAQAAIWVDSLIRLKQAGFKPKRDIKMALTCGEESEG
YNGIEDLLKNHRPLVDAEFALNEGASGLLDEQGKAVMLEVQAGEKVYQDFTLTVTNPGGH
SSRPVSPNAIYQLSAALDRIGAYQFPPRFNDATRGYFTQMQARVTPEQAAAMKTLVADVN
DPAALALITKDRTWNSMLRTTCVATMVSAGHAPNALPQRATANINCRILPGTPIDEVKAK
LTELAADPAVAVTLAHSSKPASPPPPLTPAIMAPIQKNAAKLWPGVPILPVMSTGATDAV
HTSAAGIPTYGVTGLFHGPEGTGAHGLNERMRVKSLYEGRDFLHGLIQDYAGGK