Protein Info for CCNA_03280 in Caulobacter crescentus NA1000

Annotation: pyruvate ferredoxin/flavodoxin oxidoreductase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1146 PF01558: POR" amino acids 728 to 913 (186 residues), 66.6 bits, see alignment E=3.2e-22 PF20169: DUF6537" amino acids 937 to 1136 (200 residues), 214.7 bits, see alignment E=1.4e-67

Best Hits

KEGG orthology group: K04090, indolepyruvate ferredoxin oxidoreductase [EC: 1.2.7.8] (inferred from 100% identity to ccs:CCNA_03280)

Predicted SEED Role

"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits" in subsystem Aromatic amino acid interconversions with aryl acids

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.7.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CCR2 at UniProt or InterPro

Protein Sequence (1146 amino acids)

>CCNA_03280 pyruvate ferredoxin/flavodoxin oxidoreductase family protein (Caulobacter crescentus NA1000)
MRHSEVTLDDKYVLEDGRAFITGVQALLRVLLDRKRLDRKAGLNTGGYLSGYRGSPLGGL
DQQAARIKKLLTAHDVVFQEGLNEDLAATAVWGSQQANLFPGALYDGVFGMWYGKAPGVD
RTGDVFKHANFAGTFPTGGVLAVAGDDHGCKSSTLPSQSEFAFQDFEMPVLSPADVQEVL
DYGLLGISMSRFSGLWTGMIALADTMDSGVTIDVSLDRHQIVVPEFAFPPGGLGIRQKDQ
PMEKERRMRLHKIPAALAFARANNIDRVVLGASHVKVGKARLGIVCQGQAYKDVLEAFTA
MGMTLQEAADLGVSIYKVGMPWPLEPLGLRAFAAGLETLMVIEHKRALIEPQARAALYDL
PAQARPRVIGKTDEKGGPLLSELGSLSVAEIALAIYDRLPQGPHMERAQAYLNRVSAAGV
AAVSLAADQARKPFFCSGCPHNTSTKLPEGSRALAGIGCHYMAGFNDPMTDLNTHMGGEG
LTWVGAAPFTSEKHVFQNLGDGTYNHSGSLAIRGAVAAGTNITYKLLYNDAVAMTGGQRA
ESGFTPAQITRQLAAEGVKKTVIVVDELERYQGVNDLAPGVEIFPRSDLMRVQEMLRETP
GTTVLLYDQTCATEKRRRRKRGSMPKATQRVFINPLVCEGCGDCSVKSNCVSVEPLATEF
GRKRKINQSSCNQDYSCVEGFCPSFITLEGAESAQSKKTPAALTAESTPLPEFEPLTGVR
KILFTGVGGTGVTTVASIMAMAAHIDGRAGSVVDMTGLAQKGGSVFSHVKIGKTEETIVG
GRVPAASADVLIACDLLVAASPEGLSLYAKDRTRAFGNSDFAPTADFVTSRDVRFDSGAM
ARRVKGATKTFDACPAQRLAETEFGDAIYANMIMVGFAWQRGVIPLSSRAVYRAIKLNGV
DAEANLQAFELGRRVAHDPSTLTVKEDTTPTPETMPLDALIAHRIAQLTAYQNAAYAQRY
ADKVAKVRAAETAVSGEDGALPLTRAAAVNLYKLMAYKDEYEVARLYTDGRFAAELAGTF
KGGKAKVWLAPPLLAPKGPDGKPKKIAFGGWMLDLAFPMMAKMKGLRGTALDIFGKTEER
RMERGLIASYETGLDRLAAGLKAESLPLAVKIAEVPQAIRGFGHVKEASVVTAKAAEAKL
WTQWAG