Protein Info for CCNA_03265 in Caulobacter crescentus NA1000

Annotation: CBS pair-family sensor histidine kinase/receiver domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 PF02518: HATPase_c" amino acids 249 to 359 (111 residues), 46.9 bits, see alignment E=3.4e-16 PF00072: Response_reg" amino acids 382 to 492 (111 residues), 90 bits, see alignment E=1.2e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_03265)

Predicted SEED Role

"sensor histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CCV4 at UniProt or InterPro

Protein Sequence (510 amino acids)

>CCNA_03265 CBS pair-family sensor histidine kinase/receiver domain protein (Caulobacter crescentus NA1000)
METLSRLIEPLAPIAPGTPSATVAAMFDANPTFAALAVVDDGAPVGLVYRDVLQGMMRVA
GPALATRPVAEIMDAKPRMVPVGTDPNTFVNALADSPTPIFRTAYVAVDADGRYAGVGGL
ASLLASHRRRQHEARDAMAIVERMAVDIGAHLDGVLAITERLEQQRLTPDAAAFVRAIGD
TSRDMGETVGRAVDLHRSVNGDLQMDAAPTRLRDFADLVEARWANRASEGGSTLLVSYDG
DPECGVEIDGERLLQVIDILVENALSAGRGMIEVRLSARAEDDRITLDCQLRDNAGGHAE
DRLRRVNDPLGGVGGQDRSEMALGVGLALAQSVVRTMGGRLIAEANRGAGLTVGFSLPLI
PAAAEAAAQDAPEPVGGRSAHILIVDDNATNRMVAEALCDMFECTSEQAVDGVEAVEMAR
SGRFDLILMDIKMPRMDGVAATRAIRELSGRSSAAPIVALTANADPADVHTYLAAGMQDV
VEKPIKPERLALVLNSLLAGADGDSAEAAA