Protein Info for CCNA_03221 in Caulobacter crescentus NA1000

Annotation: phytoene dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 PF01266: DAO" amino acids 8 to 161 (154 residues), 34.8 bits, see alignment E=5.1e-12 PF13450: NAD_binding_8" amino acids 11 to 55 (45 residues), 39.5 bits, see alignment 1.9e-13 PF01593: Amino_oxidase" amino acids 18 to 329 (312 residues), 54.5 bits, see alignment E=4.6e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_3121)

Predicted SEED Role

"Beta-carotene ketolase (EC 1.14.-.-)" in subsystem Carotenoids (EC 1.14.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.14.-.-

Use Curated BLAST to search for 1.14.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CEC1 at UniProt or InterPro

Protein Sequence (543 amino acids)

>CCNA_03221 phytoene dehydrogenase (Caulobacter crescentus NA1000)
MAVTQTRDAVIIGGGHNGLVCAFYLAKAGLKVTVCEARGVVGGAAVTEEFHPGFRNSVAS
YTVSLLNPRVIADMGLRELGLTFLERPISNFLPISDDKYIKLGGGLERTQEEFRKYSRRD
AEVLPAYYAMLDEIGDILRDLAQETPPNLGDGLPGLLRALRQGGRLAFLSRQRKRDLLDL
FTKSARDVLDGWFESEPVKAAFGFDAVVGNFASPDTPGSAYVLLHHTFGEVNGKKGAWGH
AVGGMGAITQAMAKACEAAGVEILLDAPVEAVHIDGGKAAGVQLVDGRQIMAPIVSANVN
PALLYKKLVPPSALTPDFRKAVDGYKNGSGTFRMNVALSELPSFTCLPGKETAEHHQSGI
VIAPSLDYMDAAYRDAKGQGISKAPIVEMLIPSSLDTSLAPPGQHVASLFCQQFAPELPD
GRSWDDAREAAADLIIDTVDQWAPGFKASVLGRMILSPLDLERKFGLIGGDIMHGHMSLD
QLWATRPLLGHASHRAPIAGLYMCGAGTHPGGGVSGNPGRNAAREILRDKDFATAVKLSV
VGR