Protein Info for CCNA_03208 in Caulobacter crescentus NA1000

Annotation: steroid 5-alpha reductase family enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 transmembrane" amino acids 51 to 73 (23 residues), see Phobius details amino acids 85 to 103 (19 residues), see Phobius details amino acids 109 to 128 (20 residues), see Phobius details amino acids 153 to 174 (22 residues), see Phobius details amino acids 185 to 206 (22 residues), see Phobius details amino acids 239 to 263 (25 residues), see Phobius details PF06966: DUF1295" amino acids 70 to 299 (230 residues), 268.6 bits, see alignment E=6.8e-84 PF02544: Steroid_dh" amino acids 192 to 254 (63 residues), 23 bits, see alignment E=1e-08

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_3110)

Predicted SEED Role

"FIG005069: Hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CCJ1 at UniProt or InterPro

Protein Sequence (310 amino acids)

>CCNA_03208 steroid 5-alpha reductase family enzyme (Caulobacter crescentus NA1000)
MARSAGGGGLADLVSSASVAATRRHVPHEGEDPVPTFARINRIFRPEPSMSLLTILAVNA
AVSAVAFLALWAVSLRTKDVSFIDAWWGPSMALLAWSTLLQGAHTPHGLLLTGLCTLWAA
RLGLYLLWRWRKHGADRRYVAIFAHYEKTKRWNFATTSLIIVFGLQAVLSYFVALPVQLG
QGPGVLGGLAYAGAALTIVGILFETIGDAQLTAFKANPDNAGKVMDKGLWRYTRHPNYFG
DACVWWGLYLIAAETGLGAWALPGPLLMTFLLTKWSGVPTTEGKMRKSKPGYEEYVARTS
GFVPWFPKKV