Protein Info for CCNA_03023 in Caulobacter crescentus NA1000

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 721 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF07715: Plug" amino acids 67 to 164 (98 residues), 65 bits, see alignment E=8.6e-22 TIGR01783: TonB-dependent siderophore receptor" amino acids 69 to 721 (653 residues), 336.3 bits, see alignment E=2.2e-104 PF00593: TonB_dep_Rec" amino acids 251 to 687 (437 residues), 153.5 bits, see alignment E=1.8e-48

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to ccr:CC_2928)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CAJ6 at UniProt or InterPro

Protein Sequence (721 amino acids)

>CCNA_03023 TonB-dependent receptor (Caulobacter crescentus NA1000)
MSSRLALLLSSALISGALASPALARQADTTRVDEVVITGSQVRLPPAYAGDQVAKGARVG
LLGALDTMDTPFAVTSYTEALIRNQQARSVADVLQNDPTVRVTKGFGNFQELYVVRGFPV
YSDDMTYNGLYGVLPRQFVAAELIERVDVFRGANAFLNGAAPGGSGVGGAFNLMPKRAPT
APLTRFTAGWDGGEQVYGSADIARRFGQNDAYGARVNLGLRGGETAVDGEKRDLTVLGLG
LDRRGDRARFSADLGWQDHRIEGARPTVTPLGAIPKAPSADKNFAQPWTHTDERQLFGAA
RGEFDLTDTVSAWAALGGRQGKEDNVLANPTALANGTLSAYRFDNVRKDSILSTDAGLRA
KFTTGAVGHALVASVAQVNLKSKNAYAFSNFAGFASNLYNPVAVAAPNPNFFVGGSKSDP
NVTERVKNRSVAVADTLSFLNERLLVTVGVRYQDIQTRSYDYNTGARNGAYDGDATTPAL
AAVFKPSDKISLYANYAEALVPGKIAPAQVNGVAVANVGEILSPFRGEQTEIGAKYDAGT
FGGSISLFRTTQPAEYFEASSRRYTAGGEQENQGVELTVFGQPAPGLRLLGGATWLDAQI
NRALSATLQGKTPIGVPEFQANLNLEWDVATLEGLTLEGRAVHTGSQQANTANTVSLDAW
TRFDLGARYAFEAGGKAVTLRARVENLTDRNQWVAVGGYPGANYLTLGAPRTLRLSISTD
F