Protein Info for CCNA_02858 in Caulobacter crescentus NA1000

Annotation: hipA-family phosphatidylinositol 3/4-kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 PF13657: Couple_hipA" amino acids 6 to 116 (111 residues), 62.5 bits, see alignment E=4.6e-21 PF07804: HipA_C" amino acids 170 to 407 (238 residues), 169.4 bits, see alignment E=9.3e-54

Best Hits

KEGG orthology group: K07154, (no description) (inferred from 100% identity to ccs:CCNA_02858)

Predicted SEED Role

"HIPA PROTEIN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CA56 at UniProt or InterPro

Protein Sequence (435 amino acids)

>CCNA_02858 hipA-family phosphatidylinositol 3/4-kinase (Caulobacter crescentus NA1000)
MTTVAEVRLWGSRIGAVSLEDGAETAVFAYEPSFIASGIQPAPLMMPLKAGVFSFPDLPP
RSFHGLPGMLADALPDKYGHVLIDAWLATQGRSPESFNAVERLCYTGRRGMGALEFSPMA
GPRRRVSSKIDIDALVTLASEVLTHRHDLRASFADADKADALRDILSVGTSAGGARAKAV
IAWNPATNEVRSGQVEAGAGFGYWLLKFDGVSGNRDKELADPKGYGAVEHAYGQMAAAAG
IDVAESRLLEEGGRRHFMSKRFDRLDGGGKLHMQSLAAIAHLDFNDPVANSYEQALFTMR
RMGLSMAQLEEQFRRMVFNVLARNQDDHVKNIAFLMDRAGRWRLSPAFDITWSYNPDGEW
TSRHQMSINGKRDGFDFADLEACAKTASISRGHVGRIFDEVREAVMRWPTFADAAGVDER
WRDQIGATVRLELRR