Protein Info for CCNA_02832 in Caulobacter crescentus NA1000

Annotation: microsomal dipeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF01244: Peptidase_M19" amino acids 48 to 411 (364 residues), 312.9 bits, see alignment E=1.2e-97

Best Hits

KEGG orthology group: K01273, membrane dipeptidase [EC: 3.4.13.19] (inferred from 100% identity to ccs:CCNA_02832)

Predicted SEED Role

"Dipeptidase"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.13.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CAT8 at UniProt or InterPro

Protein Sequence (422 amino acids)

>CCNA_02832 microsomal dipeptidase (Caulobacter crescentus NA1000)
MTGASMSRPLLFALTALSLTAASLAHAADKKAADKPAPSAVSKADKALHDKFLTLDTHLD
TPAHFGRPGWDIADHHEVEHDFSQVDLPRMNQGGLDGGFFVVYIGQGELTEKGYTYARDY
ALHRTIEIREMLAANPDTFEMALTSDDARRIAKAGKKFAFVSMENSWPVGEDLSLVETFY
KEGLRMAGPVHFRNNQLADSSTDPKGKIWNGYSPLGLRWLAEANRLGIVIDVSHASDDVV
DQSVALSKAPIIASHSGPKAVYDHPRNLDDARLKKIADAGGAICINSIYLTDTTPSPERK
AALEALGRAPDMKTATPEAVKAYADKRAAIDKAHPAARGDFDLYMKSMLHVLKVAGPKGV
CVGADWDGGGGMDGFEDITDLPKITARLKAEGYSDADIEAIWSGNVLRIVDAAQAYAKSV
TK