Protein Info for CCNA_02684 in Caulobacter crescentus NA1000

Annotation: cyclopropane fatty acid synthase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 347 PF02353: CMAS" amino acids 60 to 299 (240 residues), 133.5 bits, see alignment E=3.6e-42 PF13489: Methyltransf_23" amino acids 107 to 223 (117 residues), 57.3 bits, see alignment E=6.6e-19 PF05175: MTS" amino acids 115 to 219 (105 residues), 37.8 bits, see alignment E=6e-13 PF13847: Methyltransf_31" amino acids 115 to 221 (107 residues), 48.2 bits, see alignment E=4e-16 PF03848: TehB" amino acids 116 to 194 (79 residues), 24.8 bits, see alignment E=5.6e-09 PF13649: Methyltransf_25" amino acids 120 to 214 (95 residues), 62.3 bits, see alignment E=2.3e-20 PF08242: Methyltransf_12" amino acids 121 to 216 (96 residues), 46.3 bits, see alignment E=2.3e-15 PF08241: Methyltransf_11" amino acids 121 to 218 (98 residues), 54.3 bits, see alignment E=6.9e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_2601)

MetaCyc: 44% identical to phenylalkylamine N-methyltransferase (Ephedra sinica)
2.1.1.M76 [EC: 2.1.1.M76]; 2.1.1.M76 [EC: 2.1.1.M76]; 2.1.1.M76 [EC: 2.1.1.M76]; 2.1.1.M76 [EC: 2.1.1.M76]; 2.1.1.M76 [EC: 2.1.1.M76]

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase-like protein, clusters with FIG005069"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.M76

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CCT6 at UniProt or InterPro

Protein Sequence (347 amino acids)

>CCNA_02684 cyclopropane fatty acid synthase-like protein (Caulobacter crescentus NA1000)
MSLVKTAIHAFEDAPMPDLVSRAAIDFLVGDARRRLQQAPANATLAFAKEMETRPIATHT
ANANEQHYELPAPFFEAVLGPNLKYSSGLYPPGAVTLAEGEAAALRETAEHADLRDGQSV
LELGCGWGSLSLWMASRCPNSTITSVSNSASQRAFIEARAAQMGLTNLKVITADMNDFQT
DQRFDRVVSVEMFEHMSNWRALLTRVRGWLKPDGLLFLHVFTHKNTPYRFEVDDPADWIA
QYFFSGGVMPSHDLPQQFPDLFAVEQDWRWSGEHYARTARQWLENFDARRATIDPILAEV
YGKHATVWRRRWRLFFLATAGLFGHRGGEEWGVSHYRMRPVQAETAQ