Protein Info for CCNA_02673 in Caulobacter crescentus NA1000

Annotation: excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 968 TIGR00630: excinuclease ABC subunit A" amino acids 8 to 934 (927 residues), 1433.6 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 134 to 239 (106 residues), 134 bits, see alignment E=3.7e-43 PF17755: UvrA_DNA-bind" amino acids 298 to 406 (109 residues), 133.5 bits, see alignment E=7.7e-43

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 72% identity to azc:AZC_2887)

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CB72 at UniProt or InterPro

Protein Sequence (968 amino acids)

>CCNA_02673 excinuclease ABC subunit A (Caulobacter crescentus NA1000)
MAEQLNFIRVRGAREHNLKDVSVDIPRGELVVLTGLSGSGKSSLAFDTIYAEGQRRYVES
LSAYARQFLELMSKPDVDLIEGLSPAISIEQKTTSRNPRSTVGTVTEIHDYMRLLWARVG
IPYSPATGLPIESQTISQMVDKITALPEGTRLYLLAPVVRDRKGEYKKEIADWQKAGFQR
LKIDGQYYPIEDAPALDKKFKHDIDVVVDRVVTKPDMEQRLADSIEQALRLADGLAVAEF
ATLEEGETEPRRILFSERFACPVSGFTIAEIEPRLFSFNNPAGACPVCDGLGAKLAFDAD
LVIPDKDRTLHGGAVAPWAKGPSPLYTQTLQALARHYGFSMDEPWHKLSTEARDVVLNGS
KGAKIKFVYDDNARKYEVEKPFEGVLPNLERRWRETDSSWVREELGRFQSDTPCESCHGK
RLKPEALAVKVSGMDIAEVSMMAIRPARDWFAGLEGKLSDKQMEIARRILKEINDRLRFL
VDVGLDYLNMSRGSGTLSGGESQRIRLASQIGSGLTGVLYVLDEPSIGLHQRDNTRLLTS
LQGLRDLGNSVLVVEHDEEAILTADYVIDMGPAAGVHGGEIVAQGKPADIMANPKSLTGQ
YLTGAREIEVPEQRRPISKKKMLRVVGATGNNLKGVTAEIPVGTFTCITGVSGGGKSTFT
IETLYKAAARRLNNASDAPAPHERIEGLEHFDKVIDIDQSPIGRTPRSNPATYTGAFGPI
RDWFAGLPESKARGYGPGRFSFNVKGGRCEACQGDGVIKIEMHFLPDVYVTCDICKGKRY
NRETLDVVFKGKTIADVLDMTVEEAADFFKAVPPIRDKMETLKRVGLSYIKVGQQATTLS
GGEAQRVKLSKELSKRATGRTLYILDEPTTGLHFEDTKKLLEVLHELADQGNTVVVIEHN
LDVVKTADWLLDFGPEGGDGGGEIVAVGSPQDVAKVEASWTGRYLKELLDRHEERRKARV
AALKAKRA