Protein Info for CCNA_02661 in Caulobacter crescentus NA1000

Annotation: M16 family peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 935 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF00675: Peptidase_M16" amino acids 72 to 195 (124 residues), 60.9 bits, see alignment E=1.4e-20 amino acids 514 to 638 (125 residues), 39.7 bits, see alignment E=4.7e-14 PF05193: Peptidase_M16_C" amino acids 229 to 404 (176 residues), 121 bits, see alignment E=5.7e-39 amino acids 666 to 843 (178 residues), 132.2 bits, see alignment E=2e-42

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_02661)

Predicted SEED Role

"Zinc protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CB39 at UniProt or InterPro

Protein Sequence (935 amino acids)

>CCNA_02661 M16 family peptidase (Caulobacter crescentus NA1000)
MGSALLAGMTMKKLFASAAIAALVAASPALAAAPAKAVAPKAAAKVTGAMATALPTIDIP
HTTFKLSNGLTVIVHEDRKAPIVAVNIWYHVGSKNEPAGKTGFAHLFEHLMFNGSENFND
DWFKALEKLGATDMNGTTNRDRTNYFQNVPTAALDQVLWLESDRMGWLLNAIDKAKLDEQ
RGVVQNEKRQGENQPYGQAWNIITESTYPKDHPYGHTVIGSMADLDAASLDDVKTWFKNY
YGPANATLVLAGDISAAEAKAKVEKYFGDIASGPPVTRQKEWIAKRTGSQRAEMQDRVPQ
TRIYKVWNTPGFGAAETDYLDLLSDVLVSDKTSRLYKRLVFTDQSATAVGASVSPSEIGG
QFIVTLTVKPGGDPAAVEKAFDEEFQRLLRDGPTPEEVAKVRTNNLANVVRGAERIGGFG
GKSDLLAQNQVYLGDAGAYKHSLERVRNAKPADLVAAGRKWLTDGDFTLTVSPFPNYKAA
TAGADRKVMPEVGAPKPPSFVKLHRGVLSNGLKVVLAERRDTPQVQFSMVFDAGQAAETG
GKAGVSSLAVGMMTEGTTNRDNLTLSRELAQLGAEVRTGNGLDTSTVSLNTLTTTLDPAL
ALYADILRNPAYTPDDLTRRKRLSIAGIQQTKQNPNAMASRILPVLAYGPSSPYGVLSTE
ASVGAITRDDLIAYQKAWLQPKDATLIIVGDTTLEQILPKLEAQLGGWTGAQAKAKPPIT
VAPNKGAVYLIDKPGAQQSMLMVGNLVPPRNPSDEAAIDVMNTLFGGDFVSRLNMNLRED
KHWSYGAGSFVRAARGTRLFQAYAPVQTDKTAESFAEARKELLGIIGDKPITAAELAKAQ
NSLTLSLPGTWETSAGVGGSISELVNFNLPDSYPENYPRDVRAVTLDTATAAAKKVIKPD
ELVWVVVGDRASVEPKLKAMGLELRIIDADGNPAK