Protein Info for CCNA_02623 in Caulobacter crescentus NA1000

Annotation: cell division protein FtsZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 TIGR00065: cell division protein FtsZ" amino acids 13 to 328 (316 residues), 410 bits, see alignment E=5.1e-127 PF00091: Tubulin" amino acids 16 to 176 (161 residues), 173.5 bits, see alignment E=6.1e-55 PF12327: FtsZ_C" amino acids 225 to 320 (96 residues), 129.6 bits, see alignment E=4.6e-42

Best Hits

Swiss-Prot: 100% identical to FTSZ_CAUVN: Cell division protein FtsZ (ftsZ) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K03531, cell division protein FtsZ (inferred from 100% identity to ccr:CC_2540)

Predicted SEED Role

"Cell division protein FtsZ (EC 3.4.24.-)" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8H080 at UniProt or InterPro

Protein Sequence (508 amino acids)

>CCNA_02623 cell division protein FtsZ (Caulobacter crescentus NA1000)
MAISLSAPRTTELKPRIVVFGVGGAGGNAVNNMIEAGLEGVEFVVANTDAQQLQFAKTDR
RIQLGVQITQGLGAGAHPEVGMSAAEESFPEIGEHLDGAHMVFITAGMGGGTGTGAAPII
AKCARERGILTVGVVTKPFHFEGRHRMRLADSGIQELQRYVDTLIVIPNQNLFRVANERT
TFAEAFGMADQVLHSGVRSITDLMVLPGLINLDFADVRTVMTEMGKAMMGTGEGTGEDRA
LMAAQNAIANPLLDEVSLKGAKAVLVNVTGGMDMTLLEVDEAANAISDQVDPEANIIFGA
AFDPSLEGVIRVSVVATGMDGASIAQIEPKPVSRNISAAPLIAETSRPAPQPEPARPTAR
YEAARPAERPVAFAPEPAPEPEIVMSAPQPEPEAELYYDEPTVAEEPRVSAAPARSVNRI
VDPLVDDVAEEPLFPENNYYEERRPQKQGGFFSMFGGGRQRYEQQASAPQAQARSAQSAR
PQLQPIETPQADDAEDLEIPSFLRRLAN