Protein Info for CCNA_02499 in Caulobacter crescentus NA1000

Annotation: type IV secretory pathway, VirB2 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 104 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 46 to 67 (22 residues), see Phobius details amino acids 77 to 99 (23 residues), see Phobius details PF04956: TrbC" amino acids 4 to 96 (93 residues), 71.9 bits, see alignment E=2.1e-24

Best Hits

KEGG orthology group: K03197, type IV secretion system protein VirB2 (inferred from 100% identity to ccr:CC_2417)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C989 at UniProt or InterPro

Protein Sequence (104 amino acids)

>CCNA_02499 type IV secretory pathway, VirB2 protein (Caulobacter crescentus NA1000)
MTLVRRLSPALALAALAAPAHAQTVQSDPAGSGPLLAALQWMQGTLLGNLATTAAVIAVA
IVGLMMLTGRIDWRRGVTVIVGAFIVFGAAAIVAGIRSIATGVQ