Protein Info for CCNA_02478 in Caulobacter crescentus NA1000

Annotation: dihydrolipoamide acetyltransferase component of acetoin cleaving system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 PF00561: Abhydrolase_1" amino acids 41 to 277 (237 residues), 100.4 bits, see alignment E=2e-32 PF12146: Hydrolase_4" amino acids 42 to 277 (236 residues), 57.4 bits, see alignment E=2.1e-19 PF12697: Abhydrolase_6" amino acids 42 to 284 (243 residues), 80.8 bits, see alignment E=3.6e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_02478)

Predicted SEED Role

"alpha/beta hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CC76 at UniProt or InterPro

Protein Sequence (300 amino acids)

>CCNA_02478 dihydrolipoamide acetyltransferase component of acetoin cleaving system (Caulobacter crescentus NA1000)
MAQSKPFMFAAYPREALMTEQWITVGDLRIRYVDSGGEGIPVFLLSGIGASLEFWSNQLE
ALGERLRLIAWDYPGHGLSDGDGRSHDPDRYAAFALDVMNALGLERVVAVGNSLGGAIAL
RMAGLAPDRVAGLMLASPAMMGPEVFLPFRLMSLPLLGELMSKPGKLSVEQQIAALFHDS
ASATEALRRIVWRNVHKDGAPQALLATMRETLWIGGVRKVHWARSRALLKSATCPILFIH
GKQDVVLPFQQSIDCAKLNPRAEVKVIDGCGHTPQIEIPETFNAEMKAFARRVDEDHATS