Protein Info for CCNA_02181 in Caulobacter crescentus NA1000

Annotation: phosphatase/phosphohexomutase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 221 PF00702: Hydrolase" amino acids 8 to 183 (176 residues), 85.1 bits, see alignment E=1.3e-27 PF13419: HAD_2" amino acids 10 to 189 (180 residues), 100.8 bits, see alignment E=1.5e-32 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 81 to 189 (109 residues), 56.6 bits, see alignment E=3.4e-19 PF13242: Hydrolase_like" amino acids 143 to 191 (49 residues), 31.7 bits, see alignment 1.8e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_02181)

Predicted SEED Role

"hydrolase, haloacid dehalogenase-like family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8E9 at UniProt or InterPro

Protein Sequence (221 amino acids)

>CCNA_02181 phosphatase/phosphohexomutase family protein (Caulobacter crescentus NA1000)
MSFPRRVEGVVFDMDGLLLDTEIVYRAAMIEAGQVFGIGFTGEIYAAMVGKTTPECGVML
RELFGETFPVQSYFERVWADVEDLLEAETRLKAGVIEILDFLDDQGLPRGIATSNGKPAV
ERYLGRFDLLPRFHAVVAHHDVVRHKPHPDPYLEAARRIGVDPAACLALEDSHPGVRAAH
AAGMMTVMVPDILDPNEEMHDKCVHIADSLHHVLDLLKASA