Protein Info for CCNA_02171 in Caulobacter crescentus NA1000

Annotation: nucleoside permease nupC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 31 to 52 (22 residues), see Phobius details amino acids 64 to 85 (22 residues), see Phobius details amino acids 98 to 121 (24 residues), see Phobius details amino acids 178 to 202 (25 residues), see Phobius details amino acids 208 to 231 (24 residues), see Phobius details amino acids 268 to 286 (19 residues), see Phobius details amino acids 302 to 320 (19 residues), see Phobius details amino acids 328 to 348 (21 residues), see Phobius details amino acids 362 to 387 (26 residues), see Phobius details amino acids 397 to 419 (23 residues), see Phobius details PF01773: Nucleos_tra2_N" amino acids 11 to 83 (73 residues), 61.8 bits, see alignment E=1.1e-20 PF07670: Gate" amino acids 103 to 202 (100 residues), 52.7 bits, see alignment E=7.7e-18 PF07662: Nucleos_tra2_C" amino acids 211 to 417 (207 residues), 219 bits, see alignment E=9.2e-69

Best Hits

KEGG orthology group: K03317, concentrative nucleoside transporter, CNT family (inferred from 100% identity to ccr:CC_2089)

Predicted SEED Role

"Nucleoside permease NupC" in subsystem Deoxyribose and Deoxynucleoside Catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8D8 at UniProt or InterPro

Protein Sequence (426 amino acids)

>CCNA_02171 nucleoside permease nupC (Caulobacter crescentus NA1000)
MFRPENVQALAGLALTLGLCWLVSENRKRFPWGLAIGAVVIQVLLVLVLFGLPQAQQMLR
GVNGAVEGLAASTQAGTAFVFGFLAGGDQPYPVSNPGAGFIFAFRVLPVILVVCALSALL
WHWKILKWLAQGFGFVFQKTLGLRGPPALATAATIFMGQVEGPIFIRAYLDKLSRSELFM
LIAVGMACVSGSTMVAYATILADVLPNAAAHVLTASIISAPAGVLLARIIVPSDPMEKSA
DLDLSTEDKTYGSSIDAVMKGTTDGLQIALNVGATLIVFVALATMVDKVLGAFPPVGGEP
LSIARGLGVVFAPLAWSMGIPWKEAGTAGGLLGVKLILTEFTAFIQLSKVGEALLDERTR
MIMTYALCGFANIGSVGMNVAGFSVLVPQRRQEVLGLVWKAMMAGFLATCLTASLVGLMP
RSLFGL