Protein Info for CCNA_02165 in Caulobacter crescentus NA1000

Annotation: lysophospholipase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF12146: Hydrolase_4" amino acids 60 to 296 (237 residues), 179.8 bits, see alignment E=8.8e-57 PF12697: Abhydrolase_6" amino acids 65 to 301 (237 residues), 33.7 bits, see alignment E=9.2e-12 PF00561: Abhydrolase_1" amino acids 68 to 167 (100 residues), 40.9 bits, see alignment E=3e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_2083)

Predicted SEED Role

"Lysophospholipase (EC 3.1.1.5)" in subsystem Triacylglycerol metabolism (EC 3.1.1.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.5

Use Curated BLAST to search for 3.1.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C8D3 at UniProt or InterPro

Protein Sequence (352 amino acids)

>CCNA_02165 lysophospholipase (Caulobacter crescentus NA1000)
MNRRALILSACAAALSACAPLRQRPELAALGFRGPRLTDEAFISFDGAHLGLMRWLPAGE
PDWVVVGLHGMNDYANAYHLAAAWWAGRGIATYALDVRGFGRSPARGVWAQPELVIEDVR
LLVEAVRERHPRAKVALAGISMGGGLAISAMATPDPPRVDKLMLFAPAVWGWSNQPLPNK
LSLWITAHAKGDWVVKPPEWLVRNVMPSDNIDELRRMGRDPLMIWGARSDTLYGLVGLME
RAWRSPGAISTPVAWFYGANDHVIPRAPTVEAVSRLKSGALTAYYPKGYHLLLVDLQAEA
VWRDAEAFLRDAPGAWPPSDVPAIPSSLAAMTALDPPKTAKRGLSQGQRSGL