Protein Info for CCNA_02121 in Caulobacter crescentus NA1000

Annotation: ATP-dependent helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 859 PF00270: DEAD" amino acids 24 to 195 (172 residues), 94.2 bits, see alignment E=1.6e-30 PF00271: Helicase_C" amino acids 291 to 392 (102 residues), 64.9 bits, see alignment E=1.5e-21 PF19306: Lhr_WH" amino acids 436 to 584 (149 residues), 114.7 bits, see alignment E=7e-37 PF08494: DEAD_assoc" amino acids 641 to 824 (184 residues), 175.8 bits, see alignment E=1.9e-55

Best Hits

KEGG orthology group: K03724, ATP-dependent helicase Lhr and Lhr-like helicase [EC: 3.6.4.-] (inferred from 100% identity to ccr:CC_2040)

Predicted SEED Role

"FIG003033: Helicase domain protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.-

Use Curated BLAST to search for 3.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9U7 at UniProt or InterPro

Protein Sequence (859 amino acids)

>CCNA_02121 ATP-dependent helicase (Caulobacter crescentus NA1000)
MLAANALPPQFQAWFAKRGWTPRDHQLAMLDKARAGRGALLIAPTGGGKTLAGFLPSLIE
LAERPPRNTPAGVHTLYISPLKALAVDVERNLLTPIREMGLPIVAESRTGDTGESRKARQ
KVRPPDILLTTPEQLALFCAWEGAREYFSDLRCVIIDEAHAIWPSKRGDLLALGLSRLQQ
FAPNMRRVGLSATVDDPDLVRKWLGVNRVENPPPRAGEVSAEPTEGASTADLQLALSGPP
GHLPRAQGRICEPDIDLVLGAGGAQPVVEVLVSGGRVPWAGHTAEHAMAEVYDIIKAAKT
ALVFVNTRFQAEFAFQRLWELNDEGLPIALHHGSLSAEQRRKVEAAMARGELRAVVCTST
LDMGIDWGDVDLVIQLAAPKGASRMVQRIGRANHRLDEPSRAIFVPASRFEMLECRAAAD
AILENHLDGEPPRTGALDVLAQHIMGCACSEPFKPTDLYDEVRSAGPYAELTWEDFEAVV
DFVSTGGYALRTYDKFRRIVQIADGLRTARNAQARQQHRMNVGAIISPAMINIRIGGGRK
PVGGRKIGEAEEGYFEQLTPGDTFVFAGQVWRYNSLVGADAYVSPAPNDDPKMPSWGGSK
FPLSTYLAERVRQMMHDEREWSALPGDVQEWLSWQKIRSAIPAEGEMLLETFPRGKRFHM
VCYPFDGRLAHTTLAMLLTRRLDRLGVGPLGFVCNDYALNLWSLRPMDDLDLDELFAQDM
LGDDLEAWLDESFMMKRSFKHCALIAGLIERRHPGAEKSGRQVTFSTDLIYDVLRKHQPD
HLMLRCARLDAATGLLDIARLGDMLTRVRGRIRHVALDRVSPFAVPMMLEIGRERAPGDA
AGEMILAEAEADLIAEARP