Protein Info for CCNA_02042 in Caulobacter crescentus NA1000

Annotation: trigger factor chaperone

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 PF05697: Trigger_N" amino acids 3 to 151 (149 residues), 126.3 bits, see alignment E=1.8e-40 TIGR00115: trigger factor" amino acids 14 to 426 (413 residues), 426.2 bits, see alignment E=6.1e-132 PF00254: FKBP_C" amino acids 167 to 243 (77 residues), 58.7 bits, see alignment E=9.1e-20 PF05698: Trigger_C" amino acids 271 to 427 (157 residues), 148.6 bits, see alignment E=2.5e-47

Best Hits

Swiss-Prot: 100% identical to TIG_CAUVC: Trigger factor (tig) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K03545, trigger factor (inferred from 100% identity to ccr:CC_1964)

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8GX17 at UniProt or InterPro

Protein Sequence (454 amino acids)

>CCNA_02042 trigger factor chaperone (Caulobacter crescentus NA1000)
MSMQIVEKSGEGLSRVFGVTVPASELATRLEARIAEVAPQMNVKGFRPGKVPTAHVRRLY
GKALMGEVIEQALNETTTKVLEDNKLRPAGQPELNPSSDMDKVIAGGEDLSFDLAVEVMP
EFEPIDPTSIELVKPVYKVSDEEVQEALDELAKQARTYEPRTGKSLKAKDGDQLLIDFVG
TIDGVEFAGGKAEGAELVLGSGQFIPGFEDQLVGAKPGDDVVVKVKFPEEYQAKDLAGKD
AEFATKVQEVRAPVDGKADDELAKRLGLSDLAALTELLKSNLAGRYDNSSRFKLKRALLD
VLDTKHDFPLPPRMVDAEFAGIWQQVEADKARGGLPPEDAEKTEDQLKDEYKKIAERRVR
LGLVLAEIGRKNDVVVTDQELTDAIMREARQYGAQAQQVFDMYRQRADLQAALRAPIYED
KVVDLIFGKAKIEEKEVSKDELLEEDDLPEGYGG