Protein Info for CCNA_01952 in Caulobacter crescentus NA1000

Annotation: N-acetylmuramoyl-L-alanine amidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 395 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF01520: Amidase_3" amino acids 176 to 385 (210 residues), 166.6 bits, see alignment E=2.8e-53

Best Hits

KEGG orthology group: K01448, N-acetylmuramoyl-L-alanine amidase [EC: 3.5.1.28] (inferred from 100% identity to ccr:CC_1876)

Predicted SEED Role

"N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28)" (EC 3.5.1.28)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.28

Use Curated BLAST to search for 3.5.1.28

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9I3 at UniProt or InterPro

Protein Sequence (395 amino acids)

>CCNA_01952 N-acetylmuramoyl-L-alanine amidase (Caulobacter crescentus NA1000)
MRRGLINFARMGWVRALLIVGGVTLAGVAVATAKGPAAPAGVQKVRFGGDRVETRVVIDL
DRAAAGRLLSDGMADQRLVIALPNVMVSGDLQGAGQGLVKRWLIDEAAGGARLRLDLAGK
VEIRRRFLLPPGDGATAYRYVIDLKAVDGAVAPQTPRLALASAPVKAAPLRLKKVVVIDA
GHGGKDSGAVGANIYEKEVTLAAAKSLKERLERTGRFQVVLTRETDTFVPLESRVQIARR
ADADLFISLHADSGPDATTRGASVYTLSEKGADRVGLVLEKDDWLMKANMPGRDRAVSQI
LLDLSQRATKNRSAAFAQLLLANVGEETALLRRSHRDAGFIVLLAPDVPAVLLEMGFITN
PDDEAFLSSKASRARLVDAVADSIEAYFSSGLRKS