Protein Info for CCNA_01909 in Caulobacter crescentus NA1000

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF13379: NMT1_2" amino acids 41 to 257 (217 residues), 31.7 bits, see alignment E=1.5e-11 TIGR03427: ABC transporter periplasmic binding protein, urea carboxylase region" amino acids 42 to 369 (328 residues), 562.1 bits, see alignment E=1.9e-173 PF09084: NMT1" amino acids 74 to 224 (151 residues), 31.4 bits, see alignment E=1.8e-11

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 100% identity to ccs:CCNA_01909)

Predicted SEED Role

"Urea carboxylase-related ABC transporter, periplasmic substrate-binding protein" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C925 at UniProt or InterPro

Protein Sequence (369 amino acids)

>CCNA_01909 ABC transporter substrate-binding protein (Caulobacter crescentus NA1000)
MSIQFTRKRFMAALAVSVLALASCGPKAADKADPAAAAPAAKTEYRIGWTIYAGWMPWAY
AQQAGIVKKWADKYDVKIELVQINDYVESLNQFSAGKLDGVTATNMDALTVPAAAGKDTT
VLMIGDYSNGNDGLVLKDGATLADVKGRPVNLVELSVSHYLLARALEKAGLKMSDVKTVN
TSDADIVAAFGATETKALVTWNPQLSEVKKAPGAKEVFNSAMIPGEILDGLMVSTEALKA
NPNLGKALTGIWYETLALTVAQTPEGKAAREQMAKLSGSDLAGFEAQLKTTYLYADPKAA
LAATVSPDLITANDRVRKFSFSMGLFGQGAKSVDDIGISFPGGKVLGDPNNVKLRFDPAY
VQMAADGKL