Protein Info for CCNA_01906 in Caulobacter crescentus NA1000

Annotation: allophanate hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01425: Amidase
  • amino acids 30 to 440 (411 residues), 297.1 bits, E=1.3e-92
• TIGR02713: allophanate hydrolase
  • amino acids 41 to 590 (550 residues), 761.4 bits, E=2.9e-233

Best Hits

KEGG orthology group: K01457, allophanate hydrolase [EC: 3.5.1.54] (inferred from 100% identity to ccs:CCNA_01906)

Predicted SEED Role

"Allophanate hydrolase (EC 3.5.1.54)" in subsystem Urea decomposition (EC 3.5.1.54)

MetaCyc Pathways

• uracil degradation III (5/5 steps found)
• L-citrulline degradation (3/3 steps found)
• urea degradation I (3/3 steps found)
• L-arginine degradation V (arginine deiminase pathway) (3/4 steps found)
• cyanate degradation (2/3 steps found)
• cyanuric acid degradation II (3/5 steps found)
• superpathway of allantoin degradation in yeast (3/6 steps found)
• cyanuric acid degradation I (2/5 steps found)
• superpathway of atrazine degradation (3/8 steps found)
• allantoin degradation IV (anaerobic) (3/9 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Atrazine degradation
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.54

Sequence Analysis Tools

See A0A0H3CAL6 at UniProt or InterPro

Protein Sequence (594 amino acids)

>CCNA_01906 allophanate hydrolase (Caulobacter crescentus NA1000)
MNAPRLLVGEIAAGVNAGDSAESVARSALAAIEAYDAIQPQVWTLRLPEAAVLAQARAVD
ARIAAGETLPLAGVPFAVKDNIDVADLATTAACPGFAYTAGRSATVVEQLLAAGAVLVGK
TNLDQFATGLVGTRSPYGAPRCVFNQAFVSGGSSSGSAVAVAAGLVAFALGTDTAGSGRV
PAAFNHLVGLKPSKGRWSTRGLVPACRSLDCISVFAADLDGAGRVDAVLAAFDPEDPYSR
PAPQPEPALTLAGLRVAIPRPEQRIFFGDGESEALYASAVARLQAAGAVAVEVDMAPLLD
AAKLLYSGPWVAERTAAVEPLLRAAPSAIEPTVRAIVQGGLAVTGVETFRGLYALEAYRR
AAEAVWAAADALFLPTTPTIYTVKALKAEPLALNANLGLYTNFVNLLDLSALAVPAGFRA
DGTGFGVTFIGPAFADRALLDLAAVYLETFPMAETPPLDLTPHKPGVKLAVVGAHLSGMP
LHWQLTSREARLVAATRTAPAYKLYAMAESTPPKPALVHVGDGGASILVEVYELDVAAFG
AFTAEVPAPLAIGTVTLEDGTSVKGFVAEPRALNGASDITVLGGWRAYIASLQG