Protein Info for CCNA_01886 in Caulobacter crescentus NA1000

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 966 transmembrane" amino acids 66 to 85 (20 residues), see Phobius details PF07715: Plug" amino acids 111 to 218 (108 residues), 58.7 bits, see alignment E=7.7e-20 PF00593: TonB_dep_Rec" amino acids 364 to 928 (565 residues), 110.3 bits, see alignment E=2.3e-35

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_1809)

Predicted SEED Role

"Outer membrane receptor proteins, mostly Fe transport" in subsystem Hemin transport system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C7N2 at UniProt or InterPro

Protein Sequence (966 amino acids)

>CCNA_01886 TonB-dependent receptor (Caulobacter crescentus NA1000)
MMAAVHLNYRVCDIQTPLSPGLARPRSPRLPKTDARAALQQSQMSPRRAEAYWGKRMVIS
QTLRRAALLAGASTLSLVLALPAAAQTAPAPQDGVTIDELVVTAQRREEKLQDVPIAVSA
FSNDMLSRQKIDGGPNLQLAIPNVTFAKSFYSGYNFQIRGIGTKQTAVTGDSSTGVHFNG
APLTSNRLFEAEFFDVERVEVLRGPQGTLYGRNATGGVVNVLSAKPTGEFEGMVRAEVSN
YDGRKLRGMVNIPLVADKLDLRLAGATLNRGGFVDNLGTGDKVDDRDLYSFRASLRWRPT
STIDANFVWQHFKERDSRLRTGKGLCTRDNGPSSVGGTAITNATVRGFLSAGCADASVYN
AAAYGTPNSLATLYGIIGFARGLTSGDVYGGTQPKGLDVIDSAKNPYYRAEEDVFTLNVA
WDINDKLQLNSLTSYYDGELDARQEMNRFQASTVFNSTTLAPGGLVNDPQLGASNRMSVS
DRITTPSRQWSQELRLQSSFDGPFNFSLGGLALRYDVVQSFYIMSNAFTYAAMVANGGAN
CAPGGSCVYIDPNRVPTGQGHGNYLSFQPYHLDSNALFGEVYYEATPELKFTVGLRYTDD
KKTLDNFPVKLLTPGSGLTPGTPPQLTAEFKKFTGRAGFDWKPDLGFTDDTLVYAFYSRG
YKGGGPNNIGQVATLRPFYEPEYVNAFEVGTKNTLLGGALVLNGSAFFYDYKGYQISKFV
NRISVTENIDAEIKGVELEAVWEPVKRFRMNGTVGLLDTKIKNGESIDPMNRTGGNPNLT
LVKTSGAAGCVVPTAALANLLAVIQQAPGAATVTGVSGNPSALLGACSGSFATSFGVTPT
DGVAAKLKGNELPGSPNWTASIGAQYSFDVLDGWEGTVRGDYYRQGDSYARVFNTSVDQL
KGWANANLSFRLVNDERGLEIEGYVKNVFNKRAITDVFLMDEALGQVANAVFTEPRIIGV
SLQKTF