Protein Info for CCNA_01884 in Caulobacter crescentus NA1000

Annotation: acyl-CoA dehydrogenase, short-chain specific

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 382 transmembrane" amino acids 83 to 98 (16 residues), see Phobius details PF02771: Acyl-CoA_dh_N" amino acids 6 to 117 (112 residues), 65.4 bits, see alignment E=9e-22 PF02770: Acyl-CoA_dh_M" amino acids 123 to 212 (90 residues), 45.2 bits, see alignment E=1.3e-15 PF00441: Acyl-CoA_dh_1" amino acids 226 to 374 (149 residues), 81.8 bits, see alignment E=9e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_01884)

MetaCyc: 41% identical to pimeloyl-CoA dehydrogenase small subunit (Rhodopseudomonas palustris)
Pimeloyl-CoA dehydrogenase. [EC: 1.3.1.62]

Predicted SEED Role

"Acyl-CoA dehydrogenase family protein"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.3.1.62

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9C2 at UniProt or InterPro

Protein Sequence (382 amino acids)

>CCNA_01884 acyl-CoA dehydrogenase, short-chain specific (Caulobacter crescentus NA1000)
MNFDLSEEQQLLKDSARRYGADHGDFTAWRARVERGEAYDAASWRRMADLGWLMLNVPED
DGGLGAGPTETMVVAEAVGRYLMLVPFVSTGVIAPTLLTAATEALRAHLMAGLAEGKLVI
SLADAEPNGRFDLNRIATRAEAVEGGFRLTGAKSHALDGGAADWFIVPARTTAADDSQDG
VSLFLVPAEIEGLTVMRSRAMDNRHNASLKLDGVVVPAANLIGGLGEGFPLLRDAVDRGV
VARLAEAVGAMDAVREMTMEYLKTRKQFGQTLGAFQALQHRAVDMAIACEEARSMMYLAT
LALSGAPVERRKVIAAAKARVGQTSLYVGRQAVQLHGGVGFTEELAVAHYLKRLIMIDMA
FGNADHHRAELAASLRPGAVAA