Protein Info for CCNA_01879 in Caulobacter crescentus NA1000

Annotation: NADH:flavin oxidoreductases, old yellow enzyme family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00724: Oxidored_FMN" amino acids 5 to 351 (347 residues), 185 bits, see alignment E=1.3e-58

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_1802)

Predicted SEED Role

"2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)" (EC 1.3.1.34)

Isozymes

Compare fitness of predicted isozymes for: 1.3.1.34

Use Curated BLAST to search for 1.3.1.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9B7 at UniProt or InterPro

Protein Sequence (367 amino acids)

>CCNA_01879 NADH:flavin oxidoreductases, old yellow enzyme family (Caulobacter crescentus NA1000)
MSTSSLFAPTTVAGLALRNRVVMSPMTRRFSPGGVPNQAVADYYRRRAEAGVGVIITEGV
AVDHPAAVDHADIPNFHGPALDQWKTIAASVTSAGAAFIPQLWHIGGHRSLTADPPNASA
PSLSPSGVYEPGKPFGTPATEVEIEAVIQAYAKGARDAAAIGASGVEIHGAHGYLIDQFF
WAATNQRQDRYGGDMIERLRFATEVIKACREAVGPSFPIFFRYSQFKQVDYKARLCQSPD
ELAAFLQPLVDAGVDVFDCSQRRFWEPEFEGSPLNLAGWTKTLTGKPTMTVGSVGLDGDV
VASLREGVDVIAASSLDKLDVMLDRGDFDLVGVGRALLADPHWVEKVRDGQTDGLAGFTR
AALETLV